The influence of membrane microviscosity on 5'-nucleotidase activity has been investigated on liver plasma membrane preparations from rats during aging and following diet restriction. In addition the microviscosity of membranes from old rats was changed in vitro by the Active Lipids. During aging the membrane microviscosity increased progressively and in parallel the activity of 5'-nucleotidase decreased. Diet restriction was able to slow down the modification of both parameters. The experiment performed with the Active Lipids further supports that membrane microviscosity modulated the enzyme activity.
Influence of membrane fluidity on 5'-nucleotidase activity in isolated hepatocyte plasma membrane / Pieri, C.; Falasca, M.; Moroni, F.; Recchioni, R.; Marcheselli, F.. - In: BIOCHEMISTRY INTERNATIONAL. - ISSN 0158-5231. - 25:4(1991), pp. 631-638.
Influence of membrane fluidity on 5'-nucleotidase activity in isolated hepatocyte plasma membrane
Falasca M.Investigation
;
1991-01-01
Abstract
The influence of membrane microviscosity on 5'-nucleotidase activity has been investigated on liver plasma membrane preparations from rats during aging and following diet restriction. In addition the microviscosity of membranes from old rats was changed in vitro by the Active Lipids. During aging the membrane microviscosity increased progressively and in parallel the activity of 5'-nucleotidase decreased. Diet restriction was able to slow down the modification of both parameters. The experiment performed with the Active Lipids further supports that membrane microviscosity modulated the enzyme activity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
