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IRIS
: This study aimed to assess COVID-19 vaccination-related AEs in patients with rheumatoid arthritis (RA), in the COVID-19 Vaccination in Autoimmune Diseases (COVAD)-2 study. An online international cross-sectional survey captured self-reported data on COVID-19 vaccination-related adverse events (AEs) in people with RA, autoimmune diseases (AIDs; rheumatic [r] and non-rheumatic [nr]) and healthy controls (HCs). The survey was circulated by the COVAD study group, comprising 157 collaborators across 106 countries, from February to June 2022. Delayed AEs among RA were compared with other rAIDs, nrAIDs and HCs using multivariable binary regression. A total of 7203 participants were included (1423 [19.7%] RA, 2620 [36.4%] rAIDs, 426 [5.9%] nrAIDs, 2734 [38%] HCs), with 75% female. Compared to HCs, individuals with RA reported higher overall major AEs [OR 1.3 (1.0-1.7)], and an increased number of several minor AEs. Compared to nrAIDs, people with RA had several increased reported minor AEs including myalgia and joint pain. People with active RA had increased major AEs [OR 1.8 (1.1-3.0)] and hospitalisation [OR 4.1 (1.3 - 13.3)] compared to inactive RA. RA patients without autoimmune comorbidities had significantly fewer major and minor AEs than those with other rAIDs. A decreased incidence of hospitalisation was seen in patients taking methotrexate or TNF inhibitors compared to patients not taking these medications. COVID-19 vaccination is associated with minimal to no risks of delayed AEs in patients with RA compared to HCs, and fewer compared to other rAIDs. Active RA and presence of co-existing rAIDs were associated with an increased risk of delayed AEs.
COVID-19 vaccination-related delayed adverse events among people with rheumatoid arthritis: results from the international COVAD survey
Dey, Mrinalini;Doskaliuk, Bohdana;Parodis, Ioannis;Lindblom, Julius;Wincup, Chris;Joshi, Mrudula;Dey, Dzifa;Katchamart, Wanruchada;Kadam, Esha;Sen, Parikshit;Shinjo, Samuel Katsuyuki;Nune, Arvind;Goo, Phonpen Akarawatcharangura;Ziade, Nelly;Chen, Yi Ming;Traboco, Lisa S.;Gutiérrez, Carlos Enrique Toro;Vaidya, Binit;Agarwal, Vikas;Gupta, Latika;Nikiphorou, Elena;null, null;Naveen, R;Saha, Sreoshy;Tan, Ai Lyn;Kuwana, Masataka;Yoshida, Akira;Yomono, Keina;Pauling, John D.;Makol, Ashima;Day, Jessica;Chatterjee, Tulika;Cavagna, Lorenzo;Agarwal, Vishwesh;Milchert, Marcin;Distler, Oliver;Chinoy, Hector;Valikova, Tsvetelina;Gracia-Ramos, Abraham Edgar;Knitza, Johannes;Patel, Aarat;Barman, Bhupen;Tehozol, Erick Adrian Zamora;Serrano, Jorge Rojas;La Torre, Ignacio García-De;Colunga-Pedraza, Iris J.;Merayo-Chalico, Javier;Chibuzo, Okwara Celestine;Shumnalieva, Russka;Hoff, Leonardo Santos;Kibbi, Lina;Halabi, Hussein;Hasan, A. T. M Tanveer;Caballero-Uribe, Carlo V.;Lilleker, James B.;Salim, Babur;Gheita, Tamer;Saavedra, Miguel A.;Kardes, Sinan;Andreoli, Laura;Lini, Daniele;Schreiber, Karen;Vince, Melinda Nagy;Singh, Yogesh Preet;Ranjan, Rajiv;Jain, Avinash;Pandya, Sapan C.;Pilania, Rakesh Kumar;Sharma, Aman;Manoj, M. Manesh;Gupta, Vikas;Kavadichanda, Chengappa G.;Patro, Pradeepta Sekhar;Ajmani, Sajal;Phatak, Sanat;Goswami, Rudra Prosad;Chowdhury, Abhra Chandra;Mathew, Ashish Jacob;Shenoy, Padnamabha;Asranna, Ajay;Bommakanti, Keerthi Talari;Shukla, Anuj;Pande, Arunkumar R.;Chandwar, Kunal;Ghodke, Akanksha;Boro, Hiya;Fazal, Zoha Zahid;Cansu, Döndü Üsküdar;Yıldırım, Reşit;Gasparyan, Armen Yuri;Papa, Nicoletta;Sambataro, Gianluca;Fabiola, Atzeni;Govoni, Marcello;Parisi, Simone;Bocci, Elena Bartoloni;Sebastiani, Gian Domenico;Fusaro, Enrico;Sebastiani, Marco;Quartuccio, Luca;Franceschini, Franco;Sainaghi, Pier Paolo;Orsolini, Giovanni;Angelis, Rossella;Danielli, Maria Giovanna;Venerito, Vincenzo;Grignaschi, Silvia;Giollo, Alessandro;Alluno, Alessia;Ioannone, Florenzo;Fornaro, Marco;Wibowo, Suryo Anggoro Kusumo;Loarce-Martos, Jesús;Prieto-González, Sergio;Gonzalez, Raquel Aranega;Nakashima, Ran;Sato, Shinji;Kimura, Naoki;Kaneko, Yuko;Gono, Takahisa;Tomaras, Stylianos;Proft, Fabian Nikolai;Holzer, Marie-Therese;Gromova, Margarita Aleksandrovna;Aharonov, Or;Griger, Zoltán;Hmamouchi, Ihsane;bouchti, Imane;Baba, Zineb;Giannini, Margherita;Maurier, François;Campagne, Julien;Meyer, Alain;Langguth, Daman;Limaye, Vidya;Needham, Merrilee;Srivastav, Nilesh;Hudson, Marie;Landon-Cardinal, Océane;Zuleta, Wilmer Gerardo Rojas;Arbeláez, Álvaro;Cajas, Javier;Silva, José António Pereira;Fonseca, João Eurico;Zimba, Olena;Bohdana, Doskaliuk;Ima-Edomwonyi, Uyi;Dedeke, Ibukunoluwa;Airenakho, Emorinken;Madu, Nwankwo Henry;Yerima, Abubakar;Olaosebikan, Hakeem;Becky, A.;Koussougbo, Oruma Devi;Palalane, Elisa;So, Ho;Ugarte-Gil, Manuel Francisco;Chinchay, Lyn;Bernaola, José Proaño;Pimentel, Victorio;Fathi, Hanan Mohammed;Mohammed, Reem Hamdy A.;Harifi, Ghita;Fuentes-Silva, Yurilís;Cabriza, Karoll;Losanto, Jonathan;Colaman, Nelly;Cachafeiro-Vilar, Antonio;Bautista, Generoso Guerra;Ho, Enrique Julio Giraldo;Nunez, Lilith Stange;Cristian, Vergara M.;Báez, Jossiell Then;Alonzo, Hugo;Pastelin, Carlos Benito Santiago;Salinas, Rodrigo García;Obiols, Alejandro Quiñónez;Chávez, Nilmo;Ordóñez, Andrea Bran;Llerena, Gil Alberto Reyes;Sierra-Zorita, Radames;Arrieta, Dina;Hidalgo, Eduardo Romero;Saenz, Ricardo;Idania, Escalante M.;Calapaqui, Wendy;Quezada, Ivonne;Arredondo, Gabriela
2024-01-01
Abstract
: This study aimed to assess COVID-19 vaccination-related AEs in patients with rheumatoid arthritis (RA), in the COVID-19 Vaccination in Autoimmune Diseases (COVAD)-2 study. An online international cross-sectional survey captured self-reported data on COVID-19 vaccination-related adverse events (AEs) in people with RA, autoimmune diseases (AIDs; rheumatic [r] and non-rheumatic [nr]) and healthy controls (HCs). The survey was circulated by the COVAD study group, comprising 157 collaborators across 106 countries, from February to June 2022. Delayed AEs among RA were compared with other rAIDs, nrAIDs and HCs using multivariable binary regression. A total of 7203 participants were included (1423 [19.7%] RA, 2620 [36.4%] rAIDs, 426 [5.9%] nrAIDs, 2734 [38%] HCs), with 75% female. Compared to HCs, individuals with RA reported higher overall major AEs [OR 1.3 (1.0-1.7)], and an increased number of several minor AEs. Compared to nrAIDs, people with RA had several increased reported minor AEs including myalgia and joint pain. People with active RA had increased major AEs [OR 1.8 (1.1-3.0)] and hospitalisation [OR 4.1 (1.3 - 13.3)] compared to inactive RA. RA patients without autoimmune comorbidities had significantly fewer major and minor AEs than those with other rAIDs. A decreased incidence of hospitalisation was seen in patients taking methotrexate or TNF inhibitors compared to patients not taking these medications. COVID-19 vaccination is associated with minimal to no risks of delayed AEs in patients with RA compared to HCs, and fewer compared to other rAIDs. Active RA and presence of co-existing rAIDs were associated with an increased risk of delayed AEs.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/3007216
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simulazione ASN
Il report seguente simula gli indicatori relativi alla propria produzione scientifica in relazione alle soglie ASN 2023-2025 del proprio SC/SSD. Si ricorda che il superamento dei valori soglia (almeno 2 su 3) è requisito necessario ma non sufficiente al conseguimento dell'abilitazione. La simulazione si basa sui dati IRIS e sugli indicatori bibliometrici alla data indicata e non tiene conto di eventuali periodi di congedo obbligatorio, che in sede di domanda ASN danno diritto a incrementi percentuali dei valori. La simulazione può differire dall'esito di un’eventuale domanda ASN sia per errori di catalogazione e/o dati mancanti in IRIS, sia per la variabilità dei dati bibliometrici nel tempo. Si consideri che Anvur calcola i valori degli indicatori all'ultima data utile per la presentazione delle domande.
La presente simulazione è stata realizzata sulla base delle specifiche raccolte sul tavolo ER del Focus Group IRIS coordinato dall’Università di Modena e Reggio Emilia e delle regole riportate nel DM 589/2018 e allegata Tabella A. Cineca, l’Università di Modena e Reggio Emilia e il Focus Group IRIS non si assumono alcuna responsabilità in merito all’uso che il diretto interessato o terzi faranno della simulazione. Si specifica inoltre che la simulazione contiene calcoli effettuati con dati e algoritmi di pubblico dominio e deve quindi essere considerata come un mero ausilio al calcolo svolgibile manualmente o con strumenti equivalenti.
