Doxofylline, a newer methylxanthine derivative, has garnered increasing attention for its distinct pharmacological properties and therapeutic advantages over traditional agents such as theophylline. This paper provides a comprehensive review of the pharmacological characteristics and clinical efficacy of doxofylline, elucidating why it represents a significant advancement in methylxanthine therapy. Moreover, attention is given to the economic considerations surrounding its utilization, particularly in low- and medium-income countries where access to healthcare resources is limited. The affordability, improved tolerability, and dosing convenience of doxofylline make it a promising candidate for addressing the substantial burden of asthma and COPD in resource-constrained settings.
Doxofylline: Advancing and Empowering Equitable Asthma and COPD Management Beyond Tradition / Cazzola, M.; Page, C. P.; Calzetta, L.; Rogliani, P.; Matera, M. G.. - In: ADVANCED THERAPEUTICS. - ISSN 2366-3987. - 7:8(2024). [10.1002/adtp.202400103]
Doxofylline: Advancing and Empowering Equitable Asthma and COPD Management Beyond Tradition
Calzetta L.;Rogliani P.;
2024-01-01
Abstract
Doxofylline, a newer methylxanthine derivative, has garnered increasing attention for its distinct pharmacological properties and therapeutic advantages over traditional agents such as theophylline. This paper provides a comprehensive review of the pharmacological characteristics and clinical efficacy of doxofylline, elucidating why it represents a significant advancement in methylxanthine therapy. Moreover, attention is given to the economic considerations surrounding its utilization, particularly in low- and medium-income countries where access to healthcare resources is limited. The affordability, improved tolerability, and dosing convenience of doxofylline make it a promising candidate for addressing the substantial burden of asthma and COPD in resource-constrained settings.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.