IRIS

Methotrexate (MTX) is a key anchor drug for rheumatoid arthritis (RA) management. Fibrotic interstitial lung disease (ILD) is a common complication of RA. Whether MTX exposure increases the risk of ILD in patients with RA is disputed. We aimed to evaluate the association of prior MTX use with development of RA-ILD.

Methotrexate and rheumatoid arthritis associated interstitial lung disease / Juge, Pierre-Antoine; Lee, Joyce S; Lau, Jessica; Kawano-Dourado, Leticia; Rojas Serrano, Jorge; Sebastiani, Marco; Koduri, Gouri; Matteson, Eric; Bonfiglioli, Karina; Sawamura, Marcio; Kairalla, Ronaldo; Cavagna, Lorenzo; Bozzalla Cassione, Emanuele; Manfredi, Andreina; Mejia, Mayra; Rodríguez-Henriquez, Pedro; González-Pérez, Montserrat I; Falfán-Valencia, Ramcés; Buendia-Roldán, Ivette; Pérez-Rubio, Gloria; Ebstein, Esther; Gazal, Steven; Borie, Raphaël; Ottaviani, Sébastien; Kannengiesser, Caroline; Wallaert, Benoît; Uzunhan, Yurdagul; Nunes, Hilario; Valeyre, Dominique; Saidenberg-Kermanac'h, Nathalie; Boissier, Marie-Christophe; Wemeau-Stervinou, Lidwine; Flipo, René-Marc; Marchand-Adam, Sylvain; Richette, Pascal; Allanore, Yannick; Dromer, Claire; Truchetet, Marie-Elise; Richez, Christophe; Schaeverbeke, Thierry; Lioté, Huguette; Thabut, Gabriel; Deane, Kevin D; Solomon, Joshua; Doyle, Tracy; Ryu, Jay H; Rosas, Ivan; Holers, V Michael; Boileau, Catherine; Debray, Marie-Pierre; Porcher, Raphaël; Schwartz, David A; Vassallo, Robert; Crestani, Bruno; Dieudé, Philippe. - In: EUROPEAN RESPIRATORY JOURNAL. - ISSN 0903-1936. - 57:2(2020), pp. 1-9. [10.1183/13993003.00337-2020]

Methotrexate and rheumatoid arthritis associated interstitial lung disease

Sebastiani, Marco;
2020-01-01

Abstract

Methotrexate (MTX) is a key anchor drug for rheumatoid arthritis (RA) management. Fibrotic interstitial lung disease (ILD) is a common complication of RA. Whether MTX exposure increases the risk of ILD in patients with RA is disputed. We aimed to evaluate the association of prior MTX use with development of RA-ILD.
2020
Methotrexate and rheumatoid arthritis associated interstitial lung disease / Juge, Pierre-Antoine; Lee, Joyce S; Lau, Jessica; Kawano-Dourado, Leticia; Rojas Serrano, Jorge; Sebastiani, Marco; Koduri, Gouri; Matteson, Eric; Bonfiglioli, Karina; Sawamura, Marcio; Kairalla, Ronaldo; Cavagna, Lorenzo; Bozzalla Cassione, Emanuele; Manfredi, Andreina; Mejia, Mayra; Rodríguez-Henriquez, Pedro; González-Pérez, Montserrat I; Falfán-Valencia, Ramcés; Buendia-Roldán, Ivette; Pérez-Rubio, Gloria; Ebstein, Esther; Gazal, Steven; Borie, Raphaël; Ottaviani, Sébastien; Kannengiesser, Caroline; Wallaert, Benoît; Uzunhan, Yurdagul; Nunes, Hilario; Valeyre, Dominique; Saidenberg-Kermanac'h, Nathalie; Boissier, Marie-Christophe; Wemeau-Stervinou, Lidwine; Flipo, René-Marc; Marchand-Adam, Sylvain; Richette, Pascal; Allanore, Yannick; Dromer, Claire; Truchetet, Marie-Elise; Richez, Christophe; Schaeverbeke, Thierry; Lioté, Huguette; Thabut, Gabriel; Deane, Kevin D; Solomon, Joshua; Doyle, Tracy; Ryu, Jay H; Rosas, Ivan; Holers, V Michael; Boileau, Catherine; Debray, Marie-Pierre; Porcher, Raphaël; Schwartz, David A; Vassallo, Robert; Crestani, Bruno; Dieudé, Philippe. - In: EUROPEAN RESPIRATORY JOURNAL. - ISSN 0903-1936. - 57:2(2020), pp. 1-9. [10.1183/13993003.00337-2020]
1.1 Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
Eur Respir J-2021-Juge-2000337.pdf

accesso aperto

Tipologia: Versione (PDF) editoriale
Licenza: Copyright dell'editore
Dimensione 817.74 kB
Formato Adobe PDF
Visualizza/Apri
817.74 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2977562
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 173
  • ???jsp.display-item.citation.isi??? 143
social impact