A Visayan spotted deer with progressive weight loss showed diffuse thickening and nodular changes of the pleura and peritoneum. Histology revealed a highly pleomorphic, predominantly solid neoplasm, consistent with a malignant epithelioid mesothelioma. By immunohistochemistry, expression of pan-cytokeratin, cytokeratin 5/6, and vimentin was found in tumor cells. In addition, scattered expression of calretinin, desmin and α-smooth muscle actin was present within the neoplasm. Mesotheliomas should be considered as a potential differential diagnosis for proliferative processes involving the serosa in cervids.
Malignant epithelioid mesothelioma in a Visayan spotted deer (Cervus alfredi) / M, Bazin; J, Schwinn; B, Kühl; Armando, F; A, Beineke. - In: BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT. - ISSN 0005-9366. - (2022). [DOI: 10.2376/1439-0299-2021-28]
Malignant epithelioid mesothelioma in a Visayan spotted deer (Cervus alfredi)
ARMANDO F;
2022-01-01
Abstract
A Visayan spotted deer with progressive weight loss showed diffuse thickening and nodular changes of the pleura and peritoneum. Histology revealed a highly pleomorphic, predominantly solid neoplasm, consistent with a malignant epithelioid mesothelioma. By immunohistochemistry, expression of pan-cytokeratin, cytokeratin 5/6, and vimentin was found in tumor cells. In addition, scattered expression of calretinin, desmin and α-smooth muscle actin was present within the neoplasm. Mesotheliomas should be considered as a potential differential diagnosis for proliferative processes involving the serosa in cervids.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
