Background: Over the past few decades, several surgical approaches have been proposed to treat hemorrhoids. Objective: This multicenter study aimed to compare transanal hemorrhoidal artery ligation and conventional excisional hemorrhoidectomy for grade III hemorrhoidal disease. Design: Multicenter retrospective study. Settings: Any center belonging to the Italian Society of Colorectal Surgery in which at least 30 surgical procedures per year for hemorrhoidal disease were performed was able to join the study. Patients: Clinical data from patients with Goligher's grade III hemorrhoidal disease who underwent excisional hemorrhoidectomy or hemorrhoidal artery ligation were retrospectively analyzed after a 24-month follow-up period. Main outcome measures: The primary aims were to evaluate the adoption of 2 different surgical techniques and to compare them in terms of symptoms, postoperative adverse events, and recurrences at a 24-month follow-up. Results: Data from 1681 patients were analyzed. The results of both groups were comparable in terms of postoperative clinical score by multiple regression analysis and matched case-control analysis. Patients who underwent excisional hemorrhoidectomy had a significantly higher risk of postoperative complication (adjusted OR = 1.58; p = 0.006). A secondary analysis highlighted that excisional hemorrhoidectomy performed with new devices and hemorrhoidal artery ligation reported a significantly lower risk for complications than excisional hemorrhoidectomy performed with traditional monopolar diathermy. At the 24-month follow-up assessment, recurrence was significantly higher in the hemorrhoidal artery ligation group (adjusted OR = 0.50; p = 0.001). A secondary analysis did not show a higher risk of recurrences based on the type of device. Limitations: The retrospective design and the self-reported nature of data from different centers. Conclusions: Hemorrhoidal artery ligation is an effective option for grade III hemorrhoidal disease; however, it is burdened by a high risk of recurrences. Excisional hemorrhoidectomy performed with newer devices is competitive in terms of postoperative complications.
Excisional hemorrhoidectomy versus dearterialization with mucopexy for the treatment of grade III hemorrhoidal disease: the EMODART3 multicenter study / Giuliani, Antonio; Romano, Lucia; Necozione, Stefano; Cofini, Vincenza; Di Donato, Giada; Schietroma, Mario; Carlei, Francesco; Nervini, Andrea; Gallo, Gaetano; Pietroletti, Renato; Giuliani, Alessandro; Veglia, Antonella; Antonacci, Nicola; Santandrea, Letizia; Sermonesi, Giacomo; Babic, Francesca; Ceschiutti, Giulia; Sica, Giuseppe; Bagaglini, Giulia; Divizia, Andrea; Bellato, Vittoria; Fazili, Noureen; Warusavitarne, Janindra; Boccia, Luigi; Pascariello, Annalisa; Bondurri, Andrea; Guerci, Claudio; Maffioli, Anna; Domenico Bonomo, Luca; Distefano, Giovanni; Jannaci, Alberto; Buonanno, Alberto; Cardinali, Luca; Marziali, Irene; Cocorullo, Gianfranco; Cozzani, Federico; Giuffrida, Mario; Rossini, Matteo; De Nardi, Paola; Marco Tamburini, Andrea; Francesco Feo, Claudio; Ninniri, Chiara; Folliero, Cristina; Gattesco, Davide; Mozzon, Marta; La Torre, Marco; La Torre, Filippo; De Padua, Cristina; Iannone, Immacolata; Langone, Antonio; Galleano, Raffaele; Ghazouani, Omar; Lisi, Giorgio; Campanelli, Michela; Passaro, Umberto; Lobascio, Pierluigi; Laforgia, Rita; Ottonello, Massimo; Perinotti, Roberto; Pozzo, Mauro; Piccolo, Davide; Capelli, Patrizio; Palmieri, Gerardo; Sveva Pipitone Federico, Nicoletta; Rinaldi, Marcella; Martines, Gennaro; Picciariello, Arcangelo; Selvaggi, Francesco; Maria Romano, Francesco; Selvaggi, Lucio; Tricomi, Nicola; Comparetto, Leonardo; Velci, Luigi; Virgilio, Edoardo; Annicchiarico, Alfredo; Salvemini, Carlo; Tanda, Cinzia; Federico Corona, Paolo; Porcu, Gianfranco. - In: DISEASES OF THE COLON & RECTUM. - ISSN 0012-3706. - 66:12(2023), pp. 1254-1263. [10.1097/DCR.0000000000002885]
Excisional hemorrhoidectomy versus dearterialization with mucopexy for the treatment of grade III hemorrhoidal disease: the EMODART3 multicenter study
Federico CozzaniResources
;Mario GiuffridaMembro del Collaboration Group
;Matteo RossiniMembro del Collaboration Group
;Gerardo PalmieriMembro del Collaboration Group
;Edoardo VirgilioResources
;Alfredo AnnicchiaricoMembro del Collaboration Group
;Carlo SalveminiMembro del Collaboration Group
;
2023-01-01
Abstract
Background: Over the past few decades, several surgical approaches have been proposed to treat hemorrhoids. Objective: This multicenter study aimed to compare transanal hemorrhoidal artery ligation and conventional excisional hemorrhoidectomy for grade III hemorrhoidal disease. Design: Multicenter retrospective study. Settings: Any center belonging to the Italian Society of Colorectal Surgery in which at least 30 surgical procedures per year for hemorrhoidal disease were performed was able to join the study. Patients: Clinical data from patients with Goligher's grade III hemorrhoidal disease who underwent excisional hemorrhoidectomy or hemorrhoidal artery ligation were retrospectively analyzed after a 24-month follow-up period. Main outcome measures: The primary aims were to evaluate the adoption of 2 different surgical techniques and to compare them in terms of symptoms, postoperative adverse events, and recurrences at a 24-month follow-up. Results: Data from 1681 patients were analyzed. The results of both groups were comparable in terms of postoperative clinical score by multiple regression analysis and matched case-control analysis. Patients who underwent excisional hemorrhoidectomy had a significantly higher risk of postoperative complication (adjusted OR = 1.58; p = 0.006). A secondary analysis highlighted that excisional hemorrhoidectomy performed with new devices and hemorrhoidal artery ligation reported a significantly lower risk for complications than excisional hemorrhoidectomy performed with traditional monopolar diathermy. At the 24-month follow-up assessment, recurrence was significantly higher in the hemorrhoidal artery ligation group (adjusted OR = 0.50; p = 0.001). A secondary analysis did not show a higher risk of recurrences based on the type of device. Limitations: The retrospective design and the self-reported nature of data from different centers. Conclusions: Hemorrhoidal artery ligation is an effective option for grade III hemorrhoidal disease; however, it is burdened by a high risk of recurrences. Excisional hemorrhoidectomy performed with newer devices is competitive in terms of postoperative complications.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
