Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious “black box” needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By “lifting the veil” on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.
A field guide to flow chemistry for synthetic organic chemists / Capaldo, L; Wen, Z; Noël, T. - In: CHEMICAL SCIENCE. - ISSN 2041-6520. - 14:(2023), pp. 4230-4247. [10.1039/D3SC00992K]
A field guide to flow chemistry for synthetic organic chemists
Capaldo L;
2023-01-01
Abstract
Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious “black box” needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By “lifting the veil” on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
