We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a dif-fuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an altered innate immunity with an increased risk of potentially lethal bacterial and fungal infections. Although chronic granulo-matous disease is rare, acne is a common manifestation in these patients, but there are no data about the gold standard therapy.
A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment? / Brusasco, Marco; Feliciani, Claudio; de Felici Del Giudice, Maria Beatrice. - In: DERMATOLOGY REPORTS. - ISSN 2036-7392. - 15:2(2023), p. 9631. [10.4081/dr.2023.9631]