Aim: To evaluate the efficacy of bone reconstructive procedures for the reduction of probing pocket depth (PPD), bleeding on probing (BOP) and suppuration (SOP) in peri-implantitis-related bone defects at ≥ 12-month follow-up. Materials and methods: Three databases were searched for RCTs and CCTs that compared bone reconstructive therapies to access flap surgery (Focused Question - FQ 1) and RCTs, CCTs and prospective case series that assessed the efficacy of reconstructive therapies (FQ 2). Meta-analysis was performed for FQ1 when ≥3 studies were identified, while for FQ2 a network was drawn based on RCTs with common treatment arms. Results: Seven RCTs were identified for FQ1, while 5 RCTs and 6 prospective case series for FQ2. There was no significant difference in PPD change between access flap surgery and reconstructive surgery (-0.387; p=0.325) at 12 months. Furthermore, no clear differences in terms of PPD and BOP changes resulted from the different reconstructive therapies included in the network. Only a small percentage of treated cases with any modality achieved peri-implantitis resolution, as defined by different composite outcomes. Conclusions: Reconstructive surgery does not offer significant improvements in peri-implant clinical parameters as compared to access flap surgery at 12-months. It was not possible to establish a hierarchy of efficacy amongst the different biomaterials employed for reconstructive surgery. This article is protected by copyright. All rights reserved.
The efficacy of bone reconstructive therapies in the management of peri-implantitis. A systematic review and meta-analysis / Donos, N; Calciolari, E; Ghuman, M; Baccini, M; Sousa, V; Nibali, L. - In: JOURNAL OF CLINICAL PERIODONTOLOGY. - ISSN 1600-051X. - (2023). [10.1111/jcpe.13775]
The efficacy of bone reconstructive therapies in the management of peri-implantitis. A systematic review and meta-analysis
Calciolari, E;
2023-01-01
Abstract
Aim: To evaluate the efficacy of bone reconstructive procedures for the reduction of probing pocket depth (PPD), bleeding on probing (BOP) and suppuration (SOP) in peri-implantitis-related bone defects at ≥ 12-month follow-up. Materials and methods: Three databases were searched for RCTs and CCTs that compared bone reconstructive therapies to access flap surgery (Focused Question - FQ 1) and RCTs, CCTs and prospective case series that assessed the efficacy of reconstructive therapies (FQ 2). Meta-analysis was performed for FQ1 when ≥3 studies were identified, while for FQ2 a network was drawn based on RCTs with common treatment arms. Results: Seven RCTs were identified for FQ1, while 5 RCTs and 6 prospective case series for FQ2. There was no significant difference in PPD change between access flap surgery and reconstructive surgery (-0.387; p=0.325) at 12 months. Furthermore, no clear differences in terms of PPD and BOP changes resulted from the different reconstructive therapies included in the network. Only a small percentage of treated cases with any modality achieved peri-implantitis resolution, as defined by different composite outcomes. Conclusions: Reconstructive surgery does not offer significant improvements in peri-implant clinical parameters as compared to access flap surgery at 12-months. It was not possible to establish a hierarchy of efficacy amongst the different biomaterials employed for reconstructive surgery. This article is protected by copyright. All rights reserved.File | Dimensione | Formato | |
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