Renal cell carcinomas (RCCs) are rarely described in transplanted kidneys. Available therapeutic strategies range from allograft nephrectomy to nephron-sparing procedures such as partial nephrectomy or image-guided thermal ablation. Percutaneous radiofrequency ablation (RFA) is a minimally invasive technique which provides promising oncologic outcomes in small allograft RCCs while preserving allograft function. So far, only a few cases have been reported in the transplant setting. We describe a renal transplant RCC successfully approached by ultrasound-guided RFA. A 42-year-old renal transplant recipient developed a small subcapsular allograft RCC at 11 years after transplantation. The decline in glomerular filtration rare prompted us to preserve as much parenchyma as possible. Ultrasound-guided RFA was performed under light sedation and local analgesia in a single session with a Starbust Talon needle. Postablation contrast-enhanced ultrasound displayed a 25×23 mm avascular area of complete necrosis. After 3 months gadolinium-enhanced magnetic resonance imaging confirmed the absence of viable tumor tissue and while the patient did not experience any graft function reduction (serum creatinine 2.6 mg/dL). Image-guided RFA represents a promising therapeutic modality for small allograft RCCs in recipients with mild graft dysfunction and/or elevated surgical risk. It is associated with low morbidity and parenchymal preservation. © 2011 Published by Elsevier Inc.

Percutaneous ultrasound-guided radiofrequency ablation of an allograft renal cell carcinoma: A case report / Olivani, A.; Iaria, M.; Missale, G.; Capocasale, E.; Biasini, E.; Mazzoni, M. P.; Lombardelli, L.; Luzi, E.; Frattini, A.; Pelosi, G.. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 43:(2011), pp. 3997-3999. [10.1016/j.transproceed.2011.08.089]

Percutaneous ultrasound-guided radiofrequency ablation of an allograft renal cell carcinoma: A case report

Missale G.;
2011-01-01

Abstract

Renal cell carcinomas (RCCs) are rarely described in transplanted kidneys. Available therapeutic strategies range from allograft nephrectomy to nephron-sparing procedures such as partial nephrectomy or image-guided thermal ablation. Percutaneous radiofrequency ablation (RFA) is a minimally invasive technique which provides promising oncologic outcomes in small allograft RCCs while preserving allograft function. So far, only a few cases have been reported in the transplant setting. We describe a renal transplant RCC successfully approached by ultrasound-guided RFA. A 42-year-old renal transplant recipient developed a small subcapsular allograft RCC at 11 years after transplantation. The decline in glomerular filtration rare prompted us to preserve as much parenchyma as possible. Ultrasound-guided RFA was performed under light sedation and local analgesia in a single session with a Starbust Talon needle. Postablation contrast-enhanced ultrasound displayed a 25×23 mm avascular area of complete necrosis. After 3 months gadolinium-enhanced magnetic resonance imaging confirmed the absence of viable tumor tissue and while the patient did not experience any graft function reduction (serum creatinine 2.6 mg/dL). Image-guided RFA represents a promising therapeutic modality for small allograft RCCs in recipients with mild graft dysfunction and/or elevated surgical risk. It is associated with low morbidity and parenchymal preservation. © 2011 Published by Elsevier Inc.
2011
Percutaneous ultrasound-guided radiofrequency ablation of an allograft renal cell carcinoma: A case report / Olivani, A.; Iaria, M.; Missale, G.; Capocasale, E.; Biasini, E.; Mazzoni, M. P.; Lombardelli, L.; Luzi, E.; Frattini, A.; Pelosi, G.. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 43:(2011), pp. 3997-3999. [10.1016/j.transproceed.2011.08.089]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2936051
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