Dermatoses affecting palms may represent a dermatologic challenge from both the diagnostic, and therapeutic point of view. Patients with supposedly occupational dermatitis can spend months or even years in a frustrating attempt to avoid contact with possible irritants or allergens. To underline the importance of a thorough unbiased analysis of the patient's history and clinical features, we present the iconic case of a bricklayer affected by a chronic, disabling desquamation of palms which in the end was classified as keratolysis exfoliativa (KE) attributed to ranolazine-intake, an antianginal drug. To the best of our knowledge, this specific adverse effect of drug-induced KE of palms has never been reported before in association with ranolazine.

Keratolysis exfoliativa-like eruption induced by ranolazine / Pierobon, Elena; Germi, Lerica; Sechi, Andrea; Trevisan, Giampaolo; Pezzolo, Elena; Feliciani, Claudio; Naldi, Luigi. - In: DERMATOLOGY REPORTS. - ISSN 2036-7392. - 14:1(2022). [10.4081/dr.2022.9264]

Keratolysis exfoliativa-like eruption induced by ranolazine

Pierobon, Elena
Membro del Collaboration Group
;
Feliciani, Claudio
Membro del Collaboration Group
;
2022-01-01

Abstract

Dermatoses affecting palms may represent a dermatologic challenge from both the diagnostic, and therapeutic point of view. Patients with supposedly occupational dermatitis can spend months or even years in a frustrating attempt to avoid contact with possible irritants or allergens. To underline the importance of a thorough unbiased analysis of the patient's history and clinical features, we present the iconic case of a bricklayer affected by a chronic, disabling desquamation of palms which in the end was classified as keratolysis exfoliativa (KE) attributed to ranolazine-intake, an antianginal drug. To the best of our knowledge, this specific adverse effect of drug-induced KE of palms has never been reported before in association with ranolazine.
Keratolysis exfoliativa-like eruption induced by ranolazine / Pierobon, Elena; Germi, Lerica; Sechi, Andrea; Trevisan, Giampaolo; Pezzolo, Elena; Feliciani, Claudio; Naldi, Luigi. - In: DERMATOLOGY REPORTS. - ISSN 2036-7392. - 14:1(2022). [10.4081/dr.2022.9264]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2933171
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