Sex-specific differences in DNA methylation of the oxytocin receptor gene (OXTR) have been shown in adults and are related to several mental disorders. Negative affectivity early in life is a trans-diagnostic risk marker of later psychopathology and is partly under genetic control. However, sex-specific variations in OXTR methylation (OXTRm) in infants and their associations with negative affectivity are still unknown.

Sex-dependent association between variability in infants' OXTR methylation at birth and negative affectivity at 3 months / Nazzari, Sarah; Grumi, Serena; Villa, Marco; Mambretti, Fabiana; Biasucci, Giacomo; Decembrino, Lidia; Giacchero, Roberta; Magnani, Maria Luisa; Nacinovich, Renata; Prefumo, Federico; Spinillo, Arsenio; Veggiotti, Pierangelo; Fullone, Eleonora; Giorda, Roberto; Provenzi, Livio. - In: PSYCHONEUROENDOCRINOLOGY. - ISSN 0306-4530. - 145:(2022), p. 105920. [10.1016/j.psyneuen.2022.105920]

Sex-dependent association between variability in infants' OXTR methylation at birth and negative affectivity at 3 months

Villa, Marco;Biasucci, Giacomo;
2022-01-01

Abstract

Sex-specific differences in DNA methylation of the oxytocin receptor gene (OXTR) have been shown in adults and are related to several mental disorders. Negative affectivity early in life is a trans-diagnostic risk marker of later psychopathology and is partly under genetic control. However, sex-specific variations in OXTR methylation (OXTRm) in infants and their associations with negative affectivity are still unknown.
2022
Sex-dependent association between variability in infants' OXTR methylation at birth and negative affectivity at 3 months / Nazzari, Sarah; Grumi, Serena; Villa, Marco; Mambretti, Fabiana; Biasucci, Giacomo; Decembrino, Lidia; Giacchero, Roberta; Magnani, Maria Luisa; Nacinovich, Renata; Prefumo, Federico; Spinillo, Arsenio; Veggiotti, Pierangelo; Fullone, Eleonora; Giorda, Roberto; Provenzi, Livio. - In: PSYCHONEUROENDOCRINOLOGY. - ISSN 0306-4530. - 145:(2022), p. 105920. [10.1016/j.psyneuen.2022.105920]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2933046
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