To examine whether long-term consumption of fermented milk containing a specific Lactobacillus casei may improve the health status of preschool children suffering from allergic asthma and/or rhinitis a randomized, prospective, double blind, controlled trial was conducted in 187 children 2–5 y of age. The children received for 12 mo either fermented milk (100 mL) containing Lactobacillus casei (108 cfu/mL) or placebo. The time free from and the number of episodes of asthma/rhinitis after starting intervention were the outcome measures. The number of fever or diarrhea episodes and the change in serum immunoglobulin were further assessed. No statistical difference between intervention and control group occurred in asthmatic children. In children with rhinitis, the annual number of rhinitis episodes was lower in the intervention group, mean difference (95% CI), 1.6 ( 3.15 to 0.05); the mean duration of an episode of diarrhea was lower in the intervention group, mean difference 0.81 ( 1.52 to 0.10) days. While longterm consumption of fermented milk containing Lactobacillus casei may improve the health status of children with allergic rhinitis no effect was found in asthmatic children. (Pediatr Res 62: 215–220, 2007)

A Randomized Prospective Double Blind Controlled Trial on Effects of Long-Term Consumption of Fermented Milk Containing Lactobacillus casei in Pre-School Children With Allergic Asthma and/or Rhinitis / Marcello, Giovannini; Carlo, Agostoni; Enrica, Riva; Filippo, Salvini; Antonia, Ruscitto; GIAN VINCENZO, Zuccotti; Giovanni, Radaelli; AND THE FELICITA STUDY, Group; Biasucci, G. - In: PEDIATRIC RESEARCH. - ISSN 1530-0447. - 62:(2007), pp. 215-220. [10.1203/PDR.0b013e3180a76d94]

A Randomized Prospective Double Blind Controlled Trial on Effects of Long-Term Consumption of Fermented Milk Containing Lactobacillus casei in Pre-School Children With Allergic Asthma and/or Rhinitis

BIASUCCI G
2007-01-01

Abstract

To examine whether long-term consumption of fermented milk containing a specific Lactobacillus casei may improve the health status of preschool children suffering from allergic asthma and/or rhinitis a randomized, prospective, double blind, controlled trial was conducted in 187 children 2–5 y of age. The children received for 12 mo either fermented milk (100 mL) containing Lactobacillus casei (108 cfu/mL) or placebo. The time free from and the number of episodes of asthma/rhinitis after starting intervention were the outcome measures. The number of fever or diarrhea episodes and the change in serum immunoglobulin were further assessed. No statistical difference between intervention and control group occurred in asthmatic children. In children with rhinitis, the annual number of rhinitis episodes was lower in the intervention group, mean difference (95% CI), 1.6 ( 3.15 to 0.05); the mean duration of an episode of diarrhea was lower in the intervention group, mean difference 0.81 ( 1.52 to 0.10) days. While longterm consumption of fermented milk containing Lactobacillus casei may improve the health status of children with allergic rhinitis no effect was found in asthmatic children. (Pediatr Res 62: 215–220, 2007)
A Randomized Prospective Double Blind Controlled Trial on Effects of Long-Term Consumption of Fermented Milk Containing Lactobacillus casei in Pre-School Children With Allergic Asthma and/or Rhinitis / Marcello, Giovannini; Carlo, Agostoni; Enrica, Riva; Filippo, Salvini; Antonia, Ruscitto; GIAN VINCENZO, Zuccotti; Giovanni, Radaelli; AND THE FELICITA STUDY, Group; Biasucci, G. - In: PEDIATRIC RESEARCH. - ISSN 1530-0447. - 62:(2007), pp. 215-220. [10.1203/PDR.0b013e3180a76d94]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2930920
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