Primary Central Nervous System Lymphoma (PCNSL) is an extra- nodal Non-Hodgkin Lymphoma (NHL) that arises in the brain parenchyma, eyes, meninges, or spinal cord in the absence of lym- phoma outside of the CNS at the time of the diagnosis. Pure primary leptomeningeal lymphoma (PLML) is a subtype of PCNSL, it represents less than 0.1% of all NHL. Primary dural lymphoma (PDL) is a subentity of PLML and it is described as dura mater involvement with no systemic disease. PDL represents less than 1% of all brain lymphomas. The diagnosis of PDL is very dif- ficult because the imaging appearance usually is of an extra-axial mass mimicking a meningioma [1] or a hematoma [2,3]. We report a case of PDL with immunophenotype of chronic lymphocytic leukemia/small lymphocyte lymphoma (CLL/SLL), which was ini- tially clinically diagnosed as a chronic extradural hematoma (EDH). In literature this is the third case of PDL mimicking hematoma and the seventh case of primitive CLL/SLL of the dura.
Primary dural lymphoma mimicking a chronic epidural hematoma. Differential diagnosis of two rare conditions / Iaccarino, C.; Schiavi, P.; Crafa, P.; Bronzoni, C.; Ramponi, V.; Mantenuto, G.; Cavanna, L.; Servadei, F.. - In: CLINICAL NEUROLOGY AND NEUROSURGERY. - ISSN 0303-8467. - 115:8(2013), pp. 1510-1513. [10.1016/j.clineuro.2012.12.013]
Primary dural lymphoma mimicking a chronic epidural hematoma. Differential diagnosis of two rare conditions
Crafa P.Writing – Review & Editing
;Servadei F.Membro del Collaboration Group
2013-01-01
Abstract
Primary Central Nervous System Lymphoma (PCNSL) is an extra- nodal Non-Hodgkin Lymphoma (NHL) that arises in the brain parenchyma, eyes, meninges, or spinal cord in the absence of lym- phoma outside of the CNS at the time of the diagnosis. Pure primary leptomeningeal lymphoma (PLML) is a subtype of PCNSL, it represents less than 0.1% of all NHL. Primary dural lymphoma (PDL) is a subentity of PLML and it is described as dura mater involvement with no systemic disease. PDL represents less than 1% of all brain lymphomas. The diagnosis of PDL is very dif- ficult because the imaging appearance usually is of an extra-axial mass mimicking a meningioma [1] or a hematoma [2,3]. We report a case of PDL with immunophenotype of chronic lymphocytic leukemia/small lymphocyte lymphoma (CLL/SLL), which was ini- tially clinically diagnosed as a chronic extradural hematoma (EDH). In literature this is the third case of PDL mimicking hematoma and the seventh case of primitive CLL/SLL of the dura.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
