Background and aim: Although many mental disorders have relevant proud in neurobiological dysfunctions, most intervention approaches neglect neurophysiological features or use pharmacological intervention alone. Non-invasive Brain-Computer Interfaces (BCIs), providing natural ways of modulating mood states, can be promoted as an alternative intervention to cope with neurobiological dysfunction. Methods: A BCI prototype was proposed to feedback a person’s affective state such that a closed-loop interaction between the participant’s brain responses and the musical stimuli is established. It feedbacks in real-time flickering lights matching with the individual’s brain rhythms undergo to auditory stimuli. A RCT was carried out on 15 individuals of both genders (mean age = 49.27 years) with anxiety and depressive spectrum disorders randomly assigned to 2 groups (experimental vs. active control). Results: Outcome measures revealed either a significant decrease in Hamilton Rating Scale for Depression (HAM-D) scores and gains in cognitive functions only for participants who undergone to the experimental treatment. Variability in HAM-D scores seems explained by the changes in beta 1, beta 2 and delta bands. Conversely, the rise in cognitive function scores appear associated with theta variations. Conclusions: Future work needs to validate the relationship proposed here between music and brain responses. Findings of the present study provided support to a range of research examining BCI brain modulation and contributes to the understanding of this technique as instruments to alternative therapies We believe that Neuro-Upper can be used as an effective new tool for investigating affective responses, and emotion regulation.

A randomized controlled trial (RCT) to explore the effect of audio-visual entrainment among psychological disorders / Pino, Olimpia. - In: ACTA BIOMEDICA. - ISSN 2531-6745. - 92:6(2021), pp. 1-8. [doi:10.23750/abm.v92i6.12089]

A randomized controlled trial (RCT) to explore the effect of audio-visual entrainment among psychological disorders

Olimpia Pino
Writing – Review & Editing
2021

Abstract

Background and aim: Although many mental disorders have relevant proud in neurobiological dysfunctions, most intervention approaches neglect neurophysiological features or use pharmacological intervention alone. Non-invasive Brain-Computer Interfaces (BCIs), providing natural ways of modulating mood states, can be promoted as an alternative intervention to cope with neurobiological dysfunction. Methods: A BCI prototype was proposed to feedback a person’s affective state such that a closed-loop interaction between the participant’s brain responses and the musical stimuli is established. It feedbacks in real-time flickering lights matching with the individual’s brain rhythms undergo to auditory stimuli. A RCT was carried out on 15 individuals of both genders (mean age = 49.27 years) with anxiety and depressive spectrum disorders randomly assigned to 2 groups (experimental vs. active control). Results: Outcome measures revealed either a significant decrease in Hamilton Rating Scale for Depression (HAM-D) scores and gains in cognitive functions only for participants who undergone to the experimental treatment. Variability in HAM-D scores seems explained by the changes in beta 1, beta 2 and delta bands. Conversely, the rise in cognitive function scores appear associated with theta variations. Conclusions: Future work needs to validate the relationship proposed here between music and brain responses. Findings of the present study provided support to a range of research examining BCI brain modulation and contributes to the understanding of this technique as instruments to alternative therapies We believe that Neuro-Upper can be used as an effective new tool for investigating affective responses, and emotion regulation.
A randomized controlled trial (RCT) to explore the effect of audio-visual entrainment among psychological disorders / Pino, Olimpia. - In: ACTA BIOMEDICA. - ISSN 2531-6745. - 92:6(2021), pp. 1-8. [doi:10.23750/abm.v92i6.12089]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2906985
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