Given the fundamental role played by the intestinal microbial community in influencing host health, it is not surprising that recent decades have been marked by increased efforts to determine the taxonomic composition of the human gut microbiota and its associated functions. Despite their generally accepted importance, these large-scale human-centered studies prevent an exhaustive overview of those mechanisms and factors that contribute to the mammalian gut microbiota assembly. However, Next-Generation Sequencing techniques and associated bioinformatic tools provide an exciting opportunity to rapidly expand our knowledge on the intestinal microbial communities associated with members of the Mammalia class. These non-human-focused studies established that dietary, host phylogeny, host physiology and anthropogenic influences represent the main factors driving the selection of a specific gut microbial consortium in mammals. The current review is aimed at providing a comprehensive overview on the impact that the above-mentioned factors exert on the assembly of the mammalian gut microbiota.
Creating an atlas to visualize the biodiversity of the mammalian gut microbiota / Alessandri, Giulia; Rizzo, Sonia; Ossiprandi, Maria Cristina; VAN SINDEREN, Douwe; Ventura, Marco. - In: CURRENT OPINION IN BIOTECHNOLOGY. - ISSN 0958-1669. - 73:(2022), pp. 28-33.
Creating an atlas to visualize the biodiversity of the mammalian gut microbiota
Giulia AlessandriMembro del Collaboration Group
;Maria Cristina OssiprandiMembro del Collaboration Group
;Douwe van SinderenMembro del Collaboration Group
;Marco Ventura
2022-01-01
Abstract
Given the fundamental role played by the intestinal microbial community in influencing host health, it is not surprising that recent decades have been marked by increased efforts to determine the taxonomic composition of the human gut microbiota and its associated functions. Despite their generally accepted importance, these large-scale human-centered studies prevent an exhaustive overview of those mechanisms and factors that contribute to the mammalian gut microbiota assembly. However, Next-Generation Sequencing techniques and associated bioinformatic tools provide an exciting opportunity to rapidly expand our knowledge on the intestinal microbial communities associated with members of the Mammalia class. These non-human-focused studies established that dietary, host phylogeny, host physiology and anthropogenic influences represent the main factors driving the selection of a specific gut microbial consortium in mammals. The current review is aimed at providing a comprehensive overview on the impact that the above-mentioned factors exert on the assembly of the mammalian gut microbiota.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.