Light triggers the cyclic nucleotide cascade in photoreceptor disk membranes. We report here that light-induced changes in the apparent viscosity of disk membrane suspensions can also be observed using either native disk membranes or washed membranes reconstituted with G protein and PDE. The viscosity changes are light- and GTP-dependent and require the presence of G protein and PDE. The magnitude of the viscosity change increases with increasing membrane concentration. Under the same conditions in which light elicits a change in viscosity, we observe a large increase in light scattering by the disk membrane suspension. © 1987.
Light- and nucleotide-dependent increase in apparent viscosity in a suspension of retinal disks / Caretta, A.; Stein, P. J.. - In: FEBS LETTERS. - ISSN 0014-5793. - 219:1(1987), pp. 97-102. [10.1016/0014-5793(87)81198-5]
Light- and nucleotide-dependent increase in apparent viscosity in a suspension of retinal disks
Caretta A.
Investigation
;
1987-01-01
Abstract
Light triggers the cyclic nucleotide cascade in photoreceptor disk membranes. We report here that light-induced changes in the apparent viscosity of disk membrane suspensions can also be observed using either native disk membranes or washed membranes reconstituted with G protein and PDE. The viscosity changes are light- and GTP-dependent and require the presence of G protein and PDE. The magnitude of the viscosity change increases with increasing membrane concentration. Under the same conditions in which light elicits a change in viscosity, we observe a large increase in light scattering by the disk membrane suspension. © 1987.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.