Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.

Myocardial and microvascular injury due to Coronavirus disease 2019 / Montone, R. A.; Iannaccone, G.; Meucci, M. C.; Gurgoglione, F.; Niccoli, G.. - In: EUROPEAN CARDIOLOGY. - ISSN 1758-3756. - 15(2020), p. e52. [10.15420/ecr.2020.22]

Myocardial and microvascular injury due to Coronavirus disease 2019

Niccoli G.
2020

Abstract

Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.
Myocardial and microvascular injury due to Coronavirus disease 2019 / Montone, R. A.; Iannaccone, G.; Meucci, M. C.; Gurgoglione, F.; Niccoli, G.. - In: EUROPEAN CARDIOLOGY. - ISSN 1758-3756. - 15(2020), p. e52. [10.15420/ecr.2020.22]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2885499
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