Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.

Myocardial and microvascular injury due to Coronavirus disease 2019 / Montone, R. A.; Iannaccone, G.; Meucci, M. C.; Gurgoglione, F.; Niccoli, G.. - In: EUROPEAN CARDIOLOGY. - ISSN 1758-3756. - 15:(2020), p. e52. [10.15420/ecr.2020.22]

Myocardial and microvascular injury due to Coronavirus disease 2019

Niccoli G.
2020-01-01

Abstract

Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.
2020
Myocardial and microvascular injury due to Coronavirus disease 2019 / Montone, R. A.; Iannaccone, G.; Meucci, M. C.; Gurgoglione, F.; Niccoli, G.. - In: EUROPEAN CARDIOLOGY. - ISSN 1758-3756. - 15:(2020), p. e52. [10.15420/ecr.2020.22]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2885499
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