The vinylogous aldol reactions provides access to a range of structurally diverse targets but has long remained a marginally explored area of organic synthesis. However, its applications have burgeoned in the past few years. Examples are given to demonstrate that vinylogous dienolates and their synthons have a sumptuos aldol chemistry.
Vinylogous aldol reaction: a valuable, yet understated carbon-carbon bond-forming maneuver / Casiraghi, G.; Zanardi, F.; Appendino, G.; Rassu, G.. - In: CHEMICAL REVIEWS. - ISSN 0009-2665. - 100:6(2000), pp. 1929-1972. [10.1021/cr990247i]