Objective: To evaluate the impact of selected clinical parameters on the mid-/long-term visual outcome of patients with acute retinal necrosis (ARN) Design: A retrospective cohort study Setting: Two University Hospitals (Parma, Italy; Lausanne, Switzerland). Participants: Thirty-nine non-HIV patients (39 eyes) with ARN, as confirmed by polymerase chain reaction on intraocular samples. The following potential predictors were tested using linear regression models: age, sex, etiology, best-corrected visual acuity (BCVA) on admission, delay between ARN symptom onset and treatment initiation, and surgery (performed or not). Main outcome: BCVA at the final follow up Results: Thirty-nine of 39 non-HIV patients (22 men and 17 women; mean age, 50 years) diagnosed with ARN were enrolled in the study. Etiologies were: varicella-zoster virus in 25 eyes (64%), herpes simplex viruses in the remaining 14 eyes. The average follow-up duration was 19 ± 13 months. All patients had undergone systemic antivirals; surgery was performed in 16 eyes. The mean delay between onset of visual symptoms and antiviral treatment initiation was 15 ± 31 days (range, 1-180 days). The mean BCVA at baseline was 0.83 ± 0.75 logMAR, while the mean final BCVA was 0.75 ± 0.81 logMAR. Both initial BCVA and treatment delay (TD) were significantly correlated with the final BCVA (p < 0.05). Conclusions: Initial BCVA and TD seem to be significant predictors of mid-/long-term visual outcome in non-HIV patients affected by ARN. Keywords: Acute retinal necrosis (ARN); Predictors; Treatment; Visual outcome

The original published online version contains mistake in the presentation of the first and last names of authors.The correct author names are given above.

Correction to: Visual outcome and poor prognostic factors in acute retinal necrosis syndrome (Graefe's Archive for Clinical and Experimental Ophthalmology, (2020), 258, 9, (1851-1856), 10.1007/s00417-020-04701-z) / Mora, P.; Zola, M.; Favilla, S.; Tagliavini, V.; Calzetti, G.; Carta, A.; Gandolfi, S.; Guex-Crosier, Y.. - In: GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. - ISSN 0721-832X. - 259:1(2021), pp. 277-277. [10.1007/s00417-020-04904-4]

Correction to: Visual outcome and poor prognostic factors in acute retinal necrosis syndrome (Graefe's Archive for Clinical and Experimental Ophthalmology, (2020), 258, 9, (1851-1856), 10.1007/s00417-020-04701-z)

Mora P.;Zola M.;Calzetti G.;Carta A.;Gandolfi S.;
2021

Abstract

Objective: To evaluate the impact of selected clinical parameters on the mid-/long-term visual outcome of patients with acute retinal necrosis (ARN) Design: A retrospective cohort study Setting: Two University Hospitals (Parma, Italy; Lausanne, Switzerland). Participants: Thirty-nine non-HIV patients (39 eyes) with ARN, as confirmed by polymerase chain reaction on intraocular samples. The following potential predictors were tested using linear regression models: age, sex, etiology, best-corrected visual acuity (BCVA) on admission, delay between ARN symptom onset and treatment initiation, and surgery (performed or not). Main outcome: BCVA at the final follow up Results: Thirty-nine of 39 non-HIV patients (22 men and 17 women; mean age, 50 years) diagnosed with ARN were enrolled in the study. Etiologies were: varicella-zoster virus in 25 eyes (64%), herpes simplex viruses in the remaining 14 eyes. The average follow-up duration was 19 ± 13 months. All patients had undergone systemic antivirals; surgery was performed in 16 eyes. The mean delay between onset of visual symptoms and antiviral treatment initiation was 15 ± 31 days (range, 1-180 days). The mean BCVA at baseline was 0.83 ± 0.75 logMAR, while the mean final BCVA was 0.75 ± 0.81 logMAR. Both initial BCVA and treatment delay (TD) were significantly correlated with the final BCVA (p < 0.05). Conclusions: Initial BCVA and TD seem to be significant predictors of mid-/long-term visual outcome in non-HIV patients affected by ARN. Keywords: Acute retinal necrosis (ARN); Predictors; Treatment; Visual outcome
The original published online version contains mistake in the presentation of the first and last names of authors.The correct author names are given above.
Correction to: Visual outcome and poor prognostic factors in acute retinal necrosis syndrome (Graefe's Archive for Clinical and Experimental Ophthalmology, (2020), 258, 9, (1851-1856), 10.1007/s00417-020-04701-z) / Mora, P.; Zola, M.; Favilla, S.; Tagliavini, V.; Calzetti, G.; Carta, A.; Gandolfi, S.; Guex-Crosier, Y.. - In: GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. - ISSN 0721-832X. - 259:1(2021), pp. 277-277. [10.1007/s00417-020-04904-4]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2884020
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