We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had ∼44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages

Ancient human genomes suggest three ancestral populations for present-day Europeans / Lazaridis, I; Patterson, N; Mittnik, A; Renaud, G; Mallick, S; Kirsanow, K; Sudmant, Ph; Schraiber, Jg; Castellano, S; Lipson, M; Berger, B; Economou, C; Bollongino, R; Fu, Q; Bos, Ki; Nordenfelt, S; Li, H; de Filippo, C; Prüfer, K; Sawyer, S; Posth, C; Haak, W; Hallgren, F; Fornander, E; Rohland, N; Delsate, D; Francken, M; Guinet, Jm; Wahl, J; Ayodo, G; Babiker, Ha; Bailliet, G; Balanovska, E; Balanovsky, O; Barrantes, R; Bedoya, G; Ben-Ami, H; Bene, J; Berrada, F; Bravi, Cm; Brisighelli, F; Busby, Gb; Cali, F; Churnosov, M; Cole, De; Corach, D; Damba, L; van Driem, G; Dryomov, S; Dugoujon, Jm; Fedorova, Sa; Gallego Romero, I; Gubina, M; Hammer, M; Henn, Bm; Hervig, T; Hodoglugil, U; Jha, Ar; Karachanak-Yankova, S; Khusainova, R; Khusnutdinova, E; Kittles, R; Kivisild, T; Klitz, W; Kučinskas, V; Kushniarevich, A; Laredj, L; Litvinov, S; Loukidis, T; Mahley, Rw; Melegh, B; Metspalu, E; Molina, J; Mountain, J; Näkkäläjärvi, K; Nesheva, D; Nyambo, T; Osipova, L; Parik, J; Platonov, F; Posukh, O; Romano, V; Rothhammer, F; Rudan, I; Ruizbakiev, R; Sahakyan, H; Sajantila, A; Salas, A; Starikovskaya, Eb; Tarekegn, A; Toncheva, D; Turdikulova, S; Uktveryte, I; Utevska, O; Vasquez, R; Villena, M; Voevoda, M; Winkler, Ca; Yepiskoposyan, L; Zalloua, P; Zemunik, T; Cooper, A; Capelli, C; Thomas, Mg; Ruiz-Linares, A; Tishkoff, Sa; Singh, L; Thangaraj, K; Villems, R; Comas, D; Sukernik, R; Metspalu, M; Meyer, M; Eichler, Ee; Burger, J; Slatkin, M; Pääbo, S; Kelso, J; Reich, D; Krause, J. - In: NATURE. - ISSN 1476-4687. - 513:7518(2014), pp. 409-413. [10.1038/nature13673]

Ancient human genomes suggest three ancestral populations for present-day Europeans

Capelli C;
2014-01-01

Abstract

We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had ∼44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages
2014
Ancient human genomes suggest three ancestral populations for present-day Europeans / Lazaridis, I; Patterson, N; Mittnik, A; Renaud, G; Mallick, S; Kirsanow, K; Sudmant, Ph; Schraiber, Jg; Castellano, S; Lipson, M; Berger, B; Economou, C; Bollongino, R; Fu, Q; Bos, Ki; Nordenfelt, S; Li, H; de Filippo, C; Prüfer, K; Sawyer, S; Posth, C; Haak, W; Hallgren, F; Fornander, E; Rohland, N; Delsate, D; Francken, M; Guinet, Jm; Wahl, J; Ayodo, G; Babiker, Ha; Bailliet, G; Balanovska, E; Balanovsky, O; Barrantes, R; Bedoya, G; Ben-Ami, H; Bene, J; Berrada, F; Bravi, Cm; Brisighelli, F; Busby, Gb; Cali, F; Churnosov, M; Cole, De; Corach, D; Damba, L; van Driem, G; Dryomov, S; Dugoujon, Jm; Fedorova, Sa; Gallego Romero, I; Gubina, M; Hammer, M; Henn, Bm; Hervig, T; Hodoglugil, U; Jha, Ar; Karachanak-Yankova, S; Khusainova, R; Khusnutdinova, E; Kittles, R; Kivisild, T; Klitz, W; Kučinskas, V; Kushniarevich, A; Laredj, L; Litvinov, S; Loukidis, T; Mahley, Rw; Melegh, B; Metspalu, E; Molina, J; Mountain, J; Näkkäläjärvi, K; Nesheva, D; Nyambo, T; Osipova, L; Parik, J; Platonov, F; Posukh, O; Romano, V; Rothhammer, F; Rudan, I; Ruizbakiev, R; Sahakyan, H; Sajantila, A; Salas, A; Starikovskaya, Eb; Tarekegn, A; Toncheva, D; Turdikulova, S; Uktveryte, I; Utevska, O; Vasquez, R; Villena, M; Voevoda, M; Winkler, Ca; Yepiskoposyan, L; Zalloua, P; Zemunik, T; Cooper, A; Capelli, C; Thomas, Mg; Ruiz-Linares, A; Tishkoff, Sa; Singh, L; Thangaraj, K; Villems, R; Comas, D; Sukernik, R; Metspalu, M; Meyer, M; Eichler, Ee; Burger, J; Slatkin, M; Pääbo, S; Kelso, J; Reich, D; Krause, J. - In: NATURE. - ISSN 1476-4687. - 513:7518(2014), pp. 409-413. [10.1038/nature13673]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2883380
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 886
  • ???jsp.display-item.citation.isi??? 842
social impact