Our interest in the potential of chiral tetramethoxy-resorcinarene as agents for chiral recognition has led us to synthesise twelve distally-bridged chiral resorcinarene crowns. The fascinating architecture of these partially-enclosed chiral basket molecules is evident in the solid-state structures which have been determined by single-crystal X-ray crystallography. Moreover, the enantiomers of these chiral resorcinarene crowns have been resolved via diastereomeric resolution, with the absolute configuration of the diastereomers being determined by X-ray crystallography. This work enables further exploration of these enantio-pure chiral baskets as possible chiral resolving agents.
Synthesis of Distally-Bridged Chiral Resorcinarene Crowns / Tan, D. A.; Massera, C.; Mcildowie, M. J.; Mocerino, M.. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2020:35(2020), pp. 5695-5708. [10.1002/ejoc.202000874]
Synthesis of Distally-Bridged Chiral Resorcinarene Crowns
Massera C.;
2020-01-01
Abstract
Our interest in the potential of chiral tetramethoxy-resorcinarene as agents for chiral recognition has led us to synthesise twelve distally-bridged chiral resorcinarene crowns. The fascinating architecture of these partially-enclosed chiral basket molecules is evident in the solid-state structures which have been determined by single-crystal X-ray crystallography. Moreover, the enantiomers of these chiral resorcinarene crowns have been resolved via diastereomeric resolution, with the absolute configuration of the diastereomers being determined by X-ray crystallography. This work enables further exploration of these enantio-pure chiral baskets as possible chiral resolving agents.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
