INTRODUCTION: A baseline fetal heart rate between 110 and 160 bpm is considered normal. However among normal fetuses the average baseline heart rate has been shown to diminish progressively and the 90th centile of the fetal heart rate at 40 weeks of gestation has been consistently found at around 150 bpm. The aim of our study was to assess the labor and neonatal outcome of fetuses at 40 gestational weeks or beyond, whose intrapartum baseline fetal heart rate was between 150 and 160 bpm.MATERIAL AND METHODS: Retrospective cohort study including singleton pregnancies with spontaneous onset of labor, gestational age between 40+0 and 42+0 , category I CTG trace according to the FIGO guidelines 2015 with baseline fetal heart rate between 110-160 bpm during the first 60 minutes of the active labor. Exclusion criteria were maternal hyperpyrexia at admission, fetal arrhythmias, maternal tachycardia (>110 bpm) and uterine tachysystole (>5 contractions/10 minutes). The following outcomes were compared between fetuses with a baseline ranging between 110-149 bpm and those with a baseline ranging between 150-160 bpm: incidence of meconium-stained amniotic fluid, intrapartum hyperpyrexia, mode of delivery, Apgar at 5th minute<7, arterial pH<7.1 and Neonatal Intensive Care Unit admission, incidence of a composite adverse neonatal outcome.RESULTS: One-thousand and four CTG traces were included in the analysis, 860 in Group 110-149 bpm and 144 in Group 150-160. Group 150-160 bpm had a significantly higher incidence of meconium-stained amniotic fluid (OR 2.6; 95%CI 1.8-3.8), maternal intrapartum hyperpyrexia (OR 4.7; 95%CI 1.1-14.6), urgent/emergent cesarean section for suspected fetal distress (OR 13.4; 95% CI 3.3-54.3), Apgar <7 at 5th min (OR 9.13; 95%CI 1.5-55.1) and neonatal acidemia (OR 3.5; 95%CI 1.5-55.1). Logistic regression including adjusted for potential confounders showed that fetal heart rate between 150-160 bpm is an independent predictor of meconium-stained amniotic fluid (aOR 2.2; 95% CI 1.5-3.3), cesarean section during labor for fetal distress (aOR 10.7; 95%CI 2.9-44.6), neonatal acidemia (aOR 2.6; 95%CI 1.1-6.7) and adverse composite neonatal outcome (aOR 2.6; 95% CI 1.2-5.6).CONCLUSIONS: In fetuses at 40 weeks or beyond, an intrapartum fetal heart rate baseline ranging between 150 and 160 bpm seems associated with a higher incidence of labor complications.

Intrapartum fetal heart rate between 150 and 160 bpm at or after 40 weeks and labor outcome / Ghi, Tullio; Di Pasquo, Elvira; Dall'asta, Andrea; Commare, Arianna; Melandri, Elena; Casciaro, Alessia; Fieni, Stefania; Frusca, Tiziana. - In: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. - ISSN 0001-6349. - (2020). [10.1111/aogs.14024]

Intrapartum fetal heart rate between 150 and 160 bpm at or after 40 weeks and labor outcome

Ghi, Tullio
Conceptualization
;
Dall'asta, Andrea
Membro del Collaboration Group
;
Commare, Arianna
Membro del Collaboration Group
;
Melandri, Elena
Membro del Collaboration Group
;
Casciaro, Alessia
Membro del Collaboration Group
;
Fieni, Stefania
Membro del Collaboration Group
;
Frusca, Tiziana
Conceptualization
2020

Abstract

INTRODUCTION: A baseline fetal heart rate between 110 and 160 bpm is considered normal. However among normal fetuses the average baseline heart rate has been shown to diminish progressively and the 90th centile of the fetal heart rate at 40 weeks of gestation has been consistently found at around 150 bpm. The aim of our study was to assess the labor and neonatal outcome of fetuses at 40 gestational weeks or beyond, whose intrapartum baseline fetal heart rate was between 150 and 160 bpm.MATERIAL AND METHODS: Retrospective cohort study including singleton pregnancies with spontaneous onset of labor, gestational age between 40+0 and 42+0 , category I CTG trace according to the FIGO guidelines 2015 with baseline fetal heart rate between 110-160 bpm during the first 60 minutes of the active labor. Exclusion criteria were maternal hyperpyrexia at admission, fetal arrhythmias, maternal tachycardia (>110 bpm) and uterine tachysystole (>5 contractions/10 minutes). The following outcomes were compared between fetuses with a baseline ranging between 110-149 bpm and those with a baseline ranging between 150-160 bpm: incidence of meconium-stained amniotic fluid, intrapartum hyperpyrexia, mode of delivery, Apgar at 5th minute<7, arterial pH<7.1 and Neonatal Intensive Care Unit admission, incidence of a composite adverse neonatal outcome.RESULTS: One-thousand and four CTG traces were included in the analysis, 860 in Group 110-149 bpm and 144 in Group 150-160. Group 150-160 bpm had a significantly higher incidence of meconium-stained amniotic fluid (OR 2.6; 95%CI 1.8-3.8), maternal intrapartum hyperpyrexia (OR 4.7; 95%CI 1.1-14.6), urgent/emergent cesarean section for suspected fetal distress (OR 13.4; 95% CI 3.3-54.3), Apgar <7 at 5th min (OR 9.13; 95%CI 1.5-55.1) and neonatal acidemia (OR 3.5; 95%CI 1.5-55.1). Logistic regression including adjusted for potential confounders showed that fetal heart rate between 150-160 bpm is an independent predictor of meconium-stained amniotic fluid (aOR 2.2; 95% CI 1.5-3.3), cesarean section during labor for fetal distress (aOR 10.7; 95%CI 2.9-44.6), neonatal acidemia (aOR 2.6; 95%CI 1.1-6.7) and adverse composite neonatal outcome (aOR 2.6; 95% CI 1.2-5.6).CONCLUSIONS: In fetuses at 40 weeks or beyond, an intrapartum fetal heart rate baseline ranging between 150 and 160 bpm seems associated with a higher incidence of labor complications.
Intrapartum fetal heart rate between 150 and 160 bpm at or after 40 weeks and labor outcome / Ghi, Tullio; Di Pasquo, Elvira; Dall'asta, Andrea; Commare, Arianna; Melandri, Elena; Casciaro, Alessia; Fieni, Stefania; Frusca, Tiziana. - In: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. - ISSN 0001-6349. - (2020). [10.1111/aogs.14024]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2881601
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