Aim: Evaluating the incidence and course of COVID-19 in cancer patients treated with immunotherapy. Patients & methods: We reported the influenza-like illness events with diagnosis of COVID-19 within the patient cohort enrolled in the prospective observational multicenter INVIDIa-2 study in the single center of Parma. Results: Among 53 patients, eight experienced influenza-like illness during the influenza season 2019/2020, and three of them had diagnosis of COVID-19. They were males, elderly, with cardiovascular disease. Radiological features of COVID-19 pneumonitis were found in all of three cases, although the pharyngeal swab resulted positive in only two. Two of these three patients died due to respiratory failure. Conclusion: Cancer patients are at high risk of severe events from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Clinical impact of COVID-19 in a single-center cohort of a prospective study in cancer patients receiving immunotherapy / Bersanelli, M.; Zielli, T.; Perrone, F.; Casartelli, C.; Prattico, F.; Rapacchi, E.; Camisa, R.; Tognetto, M.; Clemente, A.; Giannarelli, D.; Rebuzzi, S. E.; Leonetti, A.; Bordi, P.; Tiseo, M.; Buti, S.. - In: IMMUNOTHERAPY. - ISSN 1750-743X. - 12:15(2020), pp. 1139-1148. [10.2217/imt-2020-0211]
Clinical impact of COVID-19 in a single-center cohort of a prospective study in cancer patients receiving immunotherapy
Bersanelli M.;Casartelli C.;Leonetti A.;Bordi P.;Tiseo M.;Buti S.
2020-01-01
Abstract
Aim: Evaluating the incidence and course of COVID-19 in cancer patients treated with immunotherapy. Patients & methods: We reported the influenza-like illness events with diagnosis of COVID-19 within the patient cohort enrolled in the prospective observational multicenter INVIDIa-2 study in the single center of Parma. Results: Among 53 patients, eight experienced influenza-like illness during the influenza season 2019/2020, and three of them had diagnosis of COVID-19. They were males, elderly, with cardiovascular disease. Radiological features of COVID-19 pneumonitis were found in all of three cases, although the pharyngeal swab resulted positive in only two. Two of these three patients died due to respiratory failure. Conclusion: Cancer patients are at high risk of severe events from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.File | Dimensione | Formato | |
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