The hydroamination reaction is a convenient alternative strategy for the formation of C– N bonds. Herein, we report a new versatile and convenient protocol for the hydroamination of arylacetylenes with anilines using palladium iodide in the absence of any added ligand as catalyst. Mild conditions, excellent regio-and stereoselectivity, and high functional group tolerance are the main features of this methodology. A subsequent reduction step gives access to a wide variety of secondary aromatic amines.

PdI2 as a simple and efficient catalyst for the hydroamination of arylacetylenes with anilines / Casnati, A.; Voronov, A.; Ferrari, D. G.; Mancuso, R.; Gabriele, B.; Motti, E.; Della Ca', N.. - In: CATALYSTS. - ISSN 2073-4344. - 10:2(2020), p. 176. [10.3390/catal10020176]

PdI2 as a simple and efficient catalyst for the hydroamination of arylacetylenes with anilines

Voronov A.;Motti E.;Della Ca' N.
2020

Abstract

The hydroamination reaction is a convenient alternative strategy for the formation of C– N bonds. Herein, we report a new versatile and convenient protocol for the hydroamination of arylacetylenes with anilines using palladium iodide in the absence of any added ligand as catalyst. Mild conditions, excellent regio-and stereoselectivity, and high functional group tolerance are the main features of this methodology. A subsequent reduction step gives access to a wide variety of secondary aromatic amines.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2873753
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