In the current version of this paper, on the basis of the data shown in Table 2, the authors concluded that a single local injection of mesenchymal stem cells (MSCs) into the rat mid-palatal suture increases new bone formation (1.21-fold) by increasing the number of osteoblasts (1.13-fold) and leading to new vessel formation (1.42-fold). The findings of this pre-clinical study may support the clinical use of MSCs after maxillary expansion (as stated by the authors) but, although they suggest it, they do not demonstrate that this approach reduces the relapse rate and achieves more stable results.
Re: bone marrow mesenchymal stem cells enhance bone formation in orthodontically expanded maxillae in rats. Abdullah Ekizer, Mehmet Emir Yalvac, Tancan Uysal, Mehmet Fatih Sonmez, Fikrettin Sahin. The Angle Orthodontist. Online Early / Barenghi, L.; Barenghi, A.; DiBlasio, A.; Gandolfini, M.. - In: ANGLE ORTHODONTIST. - ISSN 0003-3219. - 85:6(2015), pp. 1084-1085. [10.2319/angl-85-06-1084-1085.1]
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