The present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide, wherein said scaffold polypeptide constrains the structure of said L2 polypeptide, or of a fragment of said L2 polypeptide. Moreover, the present invention relates to a vaccine comprising said immunogenic polypeptide. The present invention is also concerned with a method for producing an antibody against human papillomavirus. Also encompassed by the present invention is an antibody obtained by carrying out the said method.
Immunogenic polypeptides comprising a scaffold polypeptide and a L2 polypeptide or a fragment thereof (US9303082B2) / Bolchi, Angelo; Mueller, Martin; Ottonello, Simone; Rubio, Ivonne; Tommasino, Massimo. - ELETTRONICO. - (2016).
Immunogenic polypeptides comprising a scaffold polypeptide and a L2 polypeptide or a fragment thereof (US9303082B2)
BOLCHI ANGELO;OTTONELLO SIMONE;
2016-01-01
Abstract
The present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide, wherein said scaffold polypeptide constrains the structure of said L2 polypeptide, or of a fragment of said L2 polypeptide. Moreover, the present invention relates to a vaccine comprising said immunogenic polypeptide. The present invention is also concerned with a method for producing an antibody against human papillomavirus. Also encompassed by the present invention is an antibody obtained by carrying out the said method.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
