The present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide, wherein said scaffold polypeptide constrains the structure of said L2 polypeptide, or of a fragment of said L2 polypeptide. Moreover, the present invention relates to a vaccine comprising said immunogenic polypeptide. The present invention is also concerned with a method for producing an antibody against human papillomavirus. Also encompassed by the present invention is an antibody obtained by carrying out the said method.

Immunogenic polypeptides comprising a scaffold polypeptide and a L2 polypeptide or a fragment thereof (US9303082B2) / Bolchi, Angelo; Mueller, Martin; Ottonello, Simone; Rubio, Ivonne; Tommasino, Massimo. - ELETTRONICO. - (2016).

Immunogenic polypeptides comprising a scaffold polypeptide and a L2 polypeptide or a fragment thereof (US9303082B2)

BOLCHI ANGELO;OTTONELLO SIMONE;
2016

Abstract

The present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide, wherein said scaffold polypeptide constrains the structure of said L2 polypeptide, or of a fragment of said L2 polypeptide. Moreover, the present invention relates to a vaccine comprising said immunogenic polypeptide. The present invention is also concerned with a method for producing an antibody against human papillomavirus. Also encompassed by the present invention is an antibody obtained by carrying out the said method.
Immunogenic polypeptides comprising a scaffold polypeptide and a L2 polypeptide or a fragment thereof (US9303082B2) / Bolchi, Angelo; Mueller, Martin; Ottonello, Simone; Rubio, Ivonne; Tommasino, Massimo. - ELETTRONICO. - (2016).
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2871637
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