COMBINED PROPHYLACTIC AND THERAPEUTIC VACCINES The present invention relates to an immunogenic polypeptide comprising (i) a B-cell epitope, (ii) a T-cell epitope, and (iii) a scaffold polypeptide, wherein said scaffold polypeptide is a thioredoxin polypeptide. The present invention further relates to said immunogenic polypeptide for use in medicine and for use in treating and/or preventing inappropriate proliferation of cells and/or infection with an infectious agent, preferably HPV infection, as well as to polypeptides and vectors encoding said immunogenic polypeptide.
COMBINED PROPHYLACTIC AND THERAPEUTIC VACCINES / Müller, Martin; Ottonello, Simone; Zhao, Xueer. - (2019).
COMBINED PROPHYLACTIC AND THERAPEUTIC VACCINES
OTTONELLO SIMONE;
2019-01-01
Abstract
COMBINED PROPHYLACTIC AND THERAPEUTIC VACCINES The present invention relates to an immunogenic polypeptide comprising (i) a B-cell epitope, (ii) a T-cell epitope, and (iii) a scaffold polypeptide, wherein said scaffold polypeptide is a thioredoxin polypeptide. The present invention further relates to said immunogenic polypeptide for use in medicine and for use in treating and/or preventing inappropriate proliferation of cells and/or infection with an infectious agent, preferably HPV infection, as well as to polypeptides and vectors encoding said immunogenic polypeptide.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
