The invention relates to a novel VHH construct which can be bound by a complete antibody without the antigen-binding properties of said VHH construct being adversely affected. The invention also relates to an antibody construct comprising such a VHH construct and a kit, as well as to the use of same in immunodiagnostics or in therapy. The invention allows, inter alia, the existing immunity of a patient to be directed towards another antigen.
VHH CONSTRUCTS FOR DIVERTING AN IMMUNE RESPONSE / Füner, Jonas; Bolchi, Angelo; Schliebs, Erik; Ottonello, Simone. - (2018).
VHH CONSTRUCTS FOR DIVERTING AN IMMUNE RESPONSE
BOLCHI Angelo;OTTONELLO Simone
2018-01-01
Abstract
The invention relates to a novel VHH construct which can be bound by a complete antibody without the antigen-binding properties of said VHH construct being adversely affected. The invention also relates to an antibody construct comprising such a VHH construct and a kit, as well as to the use of same in immunodiagnostics or in therapy. The invention allows, inter alia, the existing immunity of a patient to be directed towards another antigen.File in questo prodotto:
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