A careful interplay between the π electrophilicity of a cationic Au I center and the basicity of the corresponding counterion allowed for the chemo- and regioselective inter- as well as intramolecular de-aromatization of 2,3-disubstituted indoles with allenamides. The silver-free bifunctional Lewis acid/Brønsted base complex [2,4-(tBu)2C 6H3O3PAuTFA] assisted the formation of a range of densely functionalized indolenines under mild conditions.

Taming gold(I)-counterion interplay in the de-aromatization of indoles with allenamides / Jia, Minqiang; Cera, Gianpiero; Perrotta, Daniele; Monari, Magda; Bandini, Marco. - In: CHEMISTRY. - ISSN 1521-3765. - 20:32(2014), pp. 9875-9878. [10.1002/chem.201403155]

Taming gold(I)-counterion interplay in the de-aromatization of indoles with allenamides

Gianpiero Cera;
2014

Abstract

A careful interplay between the π electrophilicity of a cationic Au I center and the basicity of the corresponding counterion allowed for the chemo- and regioselective inter- as well as intramolecular de-aromatization of 2,3-disubstituted indoles with allenamides. The silver-free bifunctional Lewis acid/Brønsted base complex [2,4-(tBu)2C 6H3O3PAuTFA] assisted the formation of a range of densely functionalized indolenines under mild conditions.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2865343
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 75
  • ???jsp.display-item.citation.isi??? 75
social impact