A careful interplay between the π electrophilicity of a cationic Au I center and the basicity of the corresponding counterion allowed for the chemo- and regioselective inter- as well as intramolecular de-aromatization of 2,3-disubstituted indoles with allenamides. The silver-free bifunctional Lewis acid/Brønsted base complex [2,4-(tBu)2C 6H3O3PAuTFA] assisted the formation of a range of densely functionalized indolenines under mild conditions.
Taming gold(I)-counterion interplay in the de-aromatization of indoles with allenamides / Jia, Minqiang; Cera, Gianpiero; Perrotta, Daniele; Monari, Magda; Bandini, Marco. - In: CHEMISTRY. - ISSN 1521-3765. - 20:32(2014), pp. 9875-9878. [10.1002/chem.201403155]
Taming gold(I)-counterion interplay in the de-aromatization of indoles with allenamides
Gianpiero Cera;
2014-01-01
Abstract
A careful interplay between the π electrophilicity of a cationic Au I center and the basicity of the corresponding counterion allowed for the chemo- and regioselective inter- as well as intramolecular de-aromatization of 2,3-disubstituted indoles with allenamides. The silver-free bifunctional Lewis acid/Brønsted base complex [2,4-(tBu)2C 6H3O3PAuTFA] assisted the formation of a range of densely functionalized indolenines under mild conditions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
