Triazole assistance enabled the first iron-catalyzed C−H alkynylation of arenes, heteroarenes, and alkenes. The modular TAM directing group set the stage for a sequential C−H alkynylation/annulation strategy with ample scope, enabling the iron-catalyzed assembly of isoquinolones, pyridones, pyrrolones, and isoindolinones with high levels of chemo-, site-, and regioselectivity.

Iron-Catalyzed C-H Alkynylation through Triazole Assistance: Expedient Access to Bioactive Heterocycles / Cera, G; Haven, T; Ackermann, L. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - 23:15(2017), pp. 3577-3582. [10.1002/chem.201700587]

Iron-Catalyzed C-H Alkynylation through Triazole Assistance: Expedient Access to Bioactive Heterocycles

Cera G;
2017-01-01

Abstract

Triazole assistance enabled the first iron-catalyzed C−H alkynylation of arenes, heteroarenes, and alkenes. The modular TAM directing group set the stage for a sequential C−H alkynylation/annulation strategy with ample scope, enabling the iron-catalyzed assembly of isoquinolones, pyridones, pyrrolones, and isoindolinones with high levels of chemo-, site-, and regioselectivity.
2017
Iron-Catalyzed C-H Alkynylation through Triazole Assistance: Expedient Access to Bioactive Heterocycles / Cera, G; Haven, T; Ackermann, L. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - 23:15(2017), pp. 3577-3582. [10.1002/chem.201700587]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2865304
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