Merging Synthesis and Enantioselective Functionalization of Indoles by a Gold-Catalyzed Asymmetric Cascade Reaction

Indole chemistry continues to gain credit within organic synthesis owing to the ubiquitous presence of this heteroaromatic ring in pharmaceuticals, agrochemicals, and organic functional material science.[1] Over the past few years, metal and metal-free catalysis has played a major role in the area, contributing to the development of a number of sustainable procedures for both synthesis and asymmetric decoration of the indolyl core.