The coding sequences of five human enterovirus (HEV)-C genotype 105 strains recovered in Italy, Romania and Burundi from patients with upper and lower respiratory tract infections were analysed and phylogenetically compared with other circulating HEV-C strains. The EV-C105 was closely related to EV-C109 and EV-C118 strains. The European strains were similar to other circulating EV-C105 strains, while the two African EV-C105 clustered in separate bootstrapsupported (.0.90) branches of the P2 and P3 region trees. Minor inconsistencies in the clustering pattern of EV-C105 in the capsid region (P1) and non-capsid region (P3) suggest that recombination may have occurred in EV-C105 group B viruses. In conclusion, phylogenetic analysis revealed the circulation of two distinct EV-C105 lineages in Europe and Africa. A different pattern of evolution could be hypothesized for the two EV-C105 lineages.

Circulation of two enterovirus C105 (EV-C105) lineages in Europe and Africa / A., Piralla; C., Daleno; A., Girello; Esposito, Susanna Maria Roberta; F., Baldanti. - In: JOURNAL OF GENERAL VIROLOGY. - ISSN 0022-1317. - 96:Pt 6(2015), pp. 1374-1379. [10.1099/vir.0.000088]

Circulation of two enterovirus C105 (EV-C105) lineages in Europe and Africa

Esposito, Susanna Maria Roberta;
2015-01-01

Abstract

The coding sequences of five human enterovirus (HEV)-C genotype 105 strains recovered in Italy, Romania and Burundi from patients with upper and lower respiratory tract infections were analysed and phylogenetically compared with other circulating HEV-C strains. The EV-C105 was closely related to EV-C109 and EV-C118 strains. The European strains were similar to other circulating EV-C105 strains, while the two African EV-C105 clustered in separate bootstrapsupported (.0.90) branches of the P2 and P3 region trees. Minor inconsistencies in the clustering pattern of EV-C105 in the capsid region (P1) and non-capsid region (P3) suggest that recombination may have occurred in EV-C105 group B viruses. In conclusion, phylogenetic analysis revealed the circulation of two distinct EV-C105 lineages in Europe and Africa. A different pattern of evolution could be hypothesized for the two EV-C105 lineages.
2015
Circulation of two enterovirus C105 (EV-C105) lineages in Europe and Africa / A., Piralla; C., Daleno; A., Girello; Esposito, Susanna Maria Roberta; F., Baldanti. - In: JOURNAL OF GENERAL VIROLOGY. - ISSN 0022-1317. - 96:Pt 6(2015), pp. 1374-1379. [10.1099/vir.0.000088]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2864522
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 9
social impact