Hemophagocytic syndrome (HPS) is clinically defined as a combination of fever, liver dysfunction, coagulation abnormalities, pancytopenia, progressive macrophage proliferation throughout the reticuloendothelial system, and cytokine over-production, and may be primary or secondary to infectious, auto-immune, and tumoral diseases. The most consistent association is with viral infections but, as it is still debated whether any micro-organisms are involved in its pathogenesis, we critically appraised the literature concerning HPS and its relationship with infections

Debate around infection-dependent hemophagocytic syndrome in paediatrics / Ansuini, V.; Rigante, D.; Esposito, S.. - In: BMC INFECTIOUS DISEASES. - ISSN 1471-2334. - 13:1(2013), pp. 15.1-15.8. [10.1186/1471-2334-13-15]

Debate around infection-dependent hemophagocytic syndrome in paediatrics

S. Esposito
2013-01-01

Abstract

Hemophagocytic syndrome (HPS) is clinically defined as a combination of fever, liver dysfunction, coagulation abnormalities, pancytopenia, progressive macrophage proliferation throughout the reticuloendothelial system, and cytokine over-production, and may be primary or secondary to infectious, auto-immune, and tumoral diseases. The most consistent association is with viral infections but, as it is still debated whether any micro-organisms are involved in its pathogenesis, we critically appraised the literature concerning HPS and its relationship with infections
2013
Debate around infection-dependent hemophagocytic syndrome in paediatrics / Ansuini, V.; Rigante, D.; Esposito, S.. - In: BMC INFECTIOUS DISEASES. - ISSN 1471-2334. - 13:1(2013), pp. 15.1-15.8. [10.1186/1471-2334-13-15]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2864377
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