Bifidobacteria commonly constitute the most abundant group of microorganisms in the healthy infant gut. Their intestinal establishment is believed to be maternally driven, and their acquisition has even been postulated to occur during pregnancy. In the current study, we evaluated bifidobacterial mother-to infant transmission events in a rat model by means of quantitative PCR (qPCR), as well as by Internally Transcribed Spacer (ITS) bifidobacterial profiling. The occurrence of strains supplied by mothers during pregnancy to their corresponding newborns was observed and identified by analysis immediately following C-section delivery. These findings provide intriguing support for the existence of an unknown route to facilitate bifidobacterial transfer during the very early stages of life.

Bifidobacterial Transfer from Mother to Child as Examined by an Animal ModelIn: MICROORGANISMS. - ISSN 2076-2607. - 7:(2019), pp. 1-13. [10.3390/microorganisms7090293]

Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model.

Walter Mancino;Sabrina Duranti;Leonardo Mancabelli;Rosaria Anzalone;Christian Milani;Gabriele Andrea Lugli;Luca Carnevali;Rosario Statello;Andrea Sgoifo;Douwe van Sinderen;Marco Ventura;Francesca Turroni
2019

Abstract

Bifidobacteria commonly constitute the most abundant group of microorganisms in the healthy infant gut. Their intestinal establishment is believed to be maternally driven, and their acquisition has even been postulated to occur during pregnancy. In the current study, we evaluated bifidobacterial mother-to infant transmission events in a rat model by means of quantitative PCR (qPCR), as well as by Internally Transcribed Spacer (ITS) bifidobacterial profiling. The occurrence of strains supplied by mothers during pregnancy to their corresponding newborns was observed and identified by analysis immediately following C-section delivery. These findings provide intriguing support for the existence of an unknown route to facilitate bifidobacterial transfer during the very early stages of life.
Bifidobacterial Transfer from Mother to Child as Examined by an Animal ModelIn: MICROORGANISMS. - ISSN 2076-2607. - 7:(2019), pp. 1-13. [10.3390/microorganisms7090293]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2862658
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