Neutropenic enterocolitis, or typhlitis, is an unusual acute complication of chemotherapy-induced neutropenia, characterized by inflammatory process involving colon and/or small bowel that may progress to necrosis, haemorrhage, perforation and septicaemia. Typhlitis is usually seen in the setting of severe chemotherapy-induced neutropenia for acute leukaemia. Nevertheless, it is increasingly recognized as a complication of therapy in solid tumors. We present a case of typhlitis in a patient with advanced non-small cell lung cancer (NSCLC) who received pemetrexed, as second-line chemotherapy treatment. © 2009 Elsevier Ireland Ltd. All rights reserved.
Typhlitis during second-line chemotherapy with pemetrexed in non-small cell lung cancer (NSCLC): A case report / Tiseo, M.; Gelsomino, F.; Bartolotti, M.; Barili, M. P.; Ardizzoni, A.. - In: LUNG CANCER. - ISSN 0169-5002. - 65:2(2009), pp. 251-253. [10.1016/j.lungcan.2009.02.021]
Typhlitis during second-line chemotherapy with pemetrexed in non-small cell lung cancer (NSCLC): A case report
Tiseo M.;
2009-01-01
Abstract
Neutropenic enterocolitis, or typhlitis, is an unusual acute complication of chemotherapy-induced neutropenia, characterized by inflammatory process involving colon and/or small bowel that may progress to necrosis, haemorrhage, perforation and septicaemia. Typhlitis is usually seen in the setting of severe chemotherapy-induced neutropenia for acute leukaemia. Nevertheless, it is increasingly recognized as a complication of therapy in solid tumors. We present a case of typhlitis in a patient with advanced non-small cell lung cancer (NSCLC) who received pemetrexed, as second-line chemotherapy treatment. © 2009 Elsevier Ireland Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
