3D biomaterial manufacturing strategies show an extraordinary driving force for the development of innovative therapies in the tissue engineering field. Here, the behaviour of 3D printed chitosan (CH)-based scaffolds was explored as a function of the post-printing gelation process. To this purpose, gel forming properties of different media were tested on their capability to retain 3D structure, water content, mechanical resistance and surface/internal porosity. Three different gelation media (i.e. KOH 1.5 M, Na2CO3 1.5 M, ammonia vapours) were selected and the 3D CH scaffolds were tested in terms of biocompatibility toward fibroblast as skin associated human cell line.

Study of 3D-printed chitosan scaffold features after different post-printing gelation processes / Bergonzi, C; Di Natale, A; Zimetti, F; Marchi, C; Bianchera, A; Bernini, F; Silvestri, M; Bettini, R; Elviri, L.. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 23:9(1)(2019), p. 362. [10.1038/s41598-018-36613-8]

Study of 3D-printed chitosan scaffold features after different post-printing gelation processes

Bergonzi C;Zimetti F;Marchi C;Bianchera A;Bernini F;Silvestri M;Bettini R;Elviri L.
2019-01-01

Abstract

3D biomaterial manufacturing strategies show an extraordinary driving force for the development of innovative therapies in the tissue engineering field. Here, the behaviour of 3D printed chitosan (CH)-based scaffolds was explored as a function of the post-printing gelation process. To this purpose, gel forming properties of different media were tested on their capability to retain 3D structure, water content, mechanical resistance and surface/internal porosity. Three different gelation media (i.e. KOH 1.5 M, Na2CO3 1.5 M, ammonia vapours) were selected and the 3D CH scaffolds were tested in terms of biocompatibility toward fibroblast as skin associated human cell line.
2019
Study of 3D-printed chitosan scaffold features after different post-printing gelation processes / Bergonzi, C; Di Natale, A; Zimetti, F; Marchi, C; Bianchera, A; Bernini, F; Silvestri, M; Bettini, R; Elviri, L.. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 23:9(1)(2019), p. 362. [10.1038/s41598-018-36613-8]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2857860
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