Although much has been learned about disease of the thoracic aorta, most diagnosis of thoracic aortic aneurysm (TAA) is still incidental. The importance of the genetic aspects in thoracic aortic disease is overwhelming, and today different mutations which cause TAA or alter its natural history have been discovered. Technological advance has made available testing which detects genetic mutations linked to TAA. This article analyses the genetic aspects of TAA and describes the possible role of genetic tests in the clinical setting in preventing devastating complications of TAA.

The role of genetic testing in the prevention of acute aortic dissection / Carino, Davide; Agostinelli, Andrea; Molardi, Alberto; Benassi, Filippo; Gherli, Tiziano; Nicolini, Francesco. - In: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. - ISSN 2047-4881. - 25:IS(2018), pp. 15-23. [10.1177/2047487318756433]

The role of genetic testing in the prevention of acute aortic dissection

Tiziano Gherli;Francesco Nicolini
2018

Abstract

Although much has been learned about disease of the thoracic aorta, most diagnosis of thoracic aortic aneurysm (TAA) is still incidental. The importance of the genetic aspects in thoracic aortic disease is overwhelming, and today different mutations which cause TAA or alter its natural history have been discovered. Technological advance has made available testing which detects genetic mutations linked to TAA. This article analyses the genetic aspects of TAA and describes the possible role of genetic tests in the clinical setting in preventing devastating complications of TAA.
The role of genetic testing in the prevention of acute aortic dissection / Carino, Davide; Agostinelli, Andrea; Molardi, Alberto; Benassi, Filippo; Gherli, Tiziano; Nicolini, Francesco. - In: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. - ISSN 2047-4881. - 25:IS(2018), pp. 15-23. [10.1177/2047487318756433]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2847327
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