Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localised or generalised bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarises evidence-based and expert-based recommendations (S2 level).

Bullous pemphigoid: Italian guidelines adapted from EDF/EADV guidelines / Cozzani, E.; Marzano, A. V.; Caproni, M.; Feliciani, C.; Calzavara-Pinton, P.; Alaibac, M.; Antiga, E.; Arisi, M.; Assalve, D.; Atzori, L.; Babino, G.; Balato, A.; Balato, N.; Barbagallo, T.; Fortina, A. B.; Berardesca, E.; Berti, E.; Borghi, A.; Brazzelli, V.; Brumana, M. B.; Brusati, C.; Caccavale, S.; Caldarola, G.; Campanati, A.; Caro, R. D. C.; Coati, I.; Conti, A.; Costanzo, A.; Dattola, A.; De Simone, C.; Di Cesare, A.; Di Lernia, V.; Di Zenzo, G. M.; Fania, L.; Filosa, G.; Filotico, R.; Fusano, M.; Galluccio, A. G.; Ganzetti, G.; Gisondi, P.; Guarneri, F.; Hansel, K.; Javor, S.; Laplaca, M.; Liberati, G.; Lora, V.; Merlo, G.; Nasca, M. R.; Nigro, A.; Noal, C.; Offidani, A.; Papini, M.; Parodi, A.; Patrizi, A.; Peserico, A.; Piaserico, S.; Prignano, F.; Quaglino, P.; Rossi, M.; Satta, R.; Schena, D.; Sena, P.; Simonetti, O.; Stan, T. R.; Stingeni, L.; Talamonti, M.; Tavecchio, S.; Tognetti, L.; Vascellaro, A.; Vassallo, C.; Venturini, M.; Zampetti, A.; Zanca, A.; Cutaneous Immunology group of, Sidemast. - In: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. - ISSN 1827-1820. - 153:3(2018), pp. 305-315. [10.23736/S0392-0488.18.06006-6]

Bullous pemphigoid: Italian guidelines adapted from EDF/EADV guidelines

Feliciani C.;
2018

Abstract

Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localised or generalised bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarises evidence-based and expert-based recommendations (S2 level).
Bullous pemphigoid: Italian guidelines adapted from EDF/EADV guidelines / Cozzani, E.; Marzano, A. V.; Caproni, M.; Feliciani, C.; Calzavara-Pinton, P.; Alaibac, M.; Antiga, E.; Arisi, M.; Assalve, D.; Atzori, L.; Babino, G.; Balato, A.; Balato, N.; Barbagallo, T.; Fortina, A. B.; Berardesca, E.; Berti, E.; Borghi, A.; Brazzelli, V.; Brumana, M. B.; Brusati, C.; Caccavale, S.; Caldarola, G.; Campanati, A.; Caro, R. D. C.; Coati, I.; Conti, A.; Costanzo, A.; Dattola, A.; De Simone, C.; Di Cesare, A.; Di Lernia, V.; Di Zenzo, G. M.; Fania, L.; Filosa, G.; Filotico, R.; Fusano, M.; Galluccio, A. G.; Ganzetti, G.; Gisondi, P.; Guarneri, F.; Hansel, K.; Javor, S.; Laplaca, M.; Liberati, G.; Lora, V.; Merlo, G.; Nasca, M. R.; Nigro, A.; Noal, C.; Offidani, A.; Papini, M.; Parodi, A.; Patrizi, A.; Peserico, A.; Piaserico, S.; Prignano, F.; Quaglino, P.; Rossi, M.; Satta, R.; Schena, D.; Sena, P.; Simonetti, O.; Stan, T. R.; Stingeni, L.; Talamonti, M.; Tavecchio, S.; Tognetti, L.; Vascellaro, A.; Vassallo, C.; Venturini, M.; Zampetti, A.; Zanca, A.; Cutaneous Immunology group of, Sidemast. - In: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. - ISSN 1827-1820. - 153:3(2018), pp. 305-315. [10.23736/S0392-0488.18.06006-6]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2845735
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