Gastric bicarbonate secretion has been evaluated by Feldman's method in 48 duodenal-ulcer patients. The relationship between smoking, clinical ulcer outcome (healing and recurrence) and bicarbonate secretion has been analysed. Heavy smokers secreted higher bicarbonate ions than did non-smokers. High-relapsing patients produced lower bicarbonate output. These preliminary data suggest that an impaired gastric bicarbonate secretion is associated with smoking, a well-known ulcer-associated factor; further-more, it may single out high-relapsing duodenal ulcer patients.
Gastric bicarbonate secretion in high-relapsing, smoking duodenal ulcer patients / Dal Santo, P; Vianello, F; Germana, B; Del Bianco, T; Laino, G; Grassi, S A; Plebani, M; Dotto, P; Battaglia, G; Di Mario, F. - In: HEPATO-GASTROENTEROLOGY. - ISSN 0172-6390. - 40:2(1993), p. 120-2.
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