The role of serum PG I in screening patients with chronic atrophic gastritis and gastric cancer, and in detecting peptic ulcer patients with high relapse risk, was ascertained in 276 subjects. Although not diagnostic per se. PG I was found to be under 20 Î¼g/L in patients with chronic atrophic gastritis and in some gastric cancer or partially gastrectomized patients. In patients presenting with relapsing duodenal ulcer, PG I values were significantly higher than in the non-relapsing ones, but a satisfactory identification of all the duodenal ulcer patients with high relapse risk was not possible on this basis. Even the correlation between PG I and MAO was not accurate in every subject considered. These results suggest that the value of PG I is limited to assessing patients with upper gastrointestinal diseases in which a reduction of peptic secretion, and therefore of PG I in serum, is present. Â© 1893.
Actual role of pepsinogen group I in the study of upper gastrointestinal diseases / Plebani, M.; Di Mario, F.; Vianello, F.; Farini, R.; Piccoli, A.; Lazzaretto, L.; Perobelli, L.; Naccarato, R.; Burlina, A.. - In: CLINICAL BIOCHEMISTRY. - ISSN 0009-9120. - 16:5(1983), pp. 310-312. [10.1016/S0009-9120(83)94151-6]
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