In order to ascertain the role of gastric carcinoembryonic antigen (CEA) determination in detecting patients with a risk for gastric cancer, 69 subjects were studied; 23 were referred for endoscopy because of dyspepsia but without obvious macroscopic lesions, 27 with duodenal ulcer, 11 with benign gastric ulcer, 8 with gastric cancer. The following results were obtained by subdividing the material according to the histologic interpretation of the results of gastric mucosal biopsies: (1) in the presence of minor histologic abnormalities of the gastric mucosa, CEA in gastric juice was under 100 ng/ml in all but five cases; and (2) in moderate or severe chronic atrophic gastritis (associated or otherwise with intestinal metaplasia or dysplasia), and in gastric cancer, gastric CEA ranged between 224 and 3120 ng/ml in all but two cases. Although not diagnostic for gastric cancer, gastric CEA is a promising test in detecting patients at risk, including those with dysplasia of the gastric mucosa. Cancer 52:2334â2337, 1983. Copyright © 1983 American Cancer Society
Carcinoembryonic antigen in gastric juice collected during endoscopy. Value in detecting highâ risk patients and gastric cancer / Nitti, Donato; Farini, R.; Grassi, F.; Cardin, F.; Di Mario, F.; Piccoli, A.; Vianello, F.; Farinati, F.; Favretti, F.; Lise, M.; Naccarato Md, R.. - In: CANCER. - ISSN 0008-543X. - 52:12(1983), pp. 2334-2337. [10.1002/1097-0142(19831215)52:12<2334::AID-CNCR2820521228>3.0.CO;2-7]
Carcinoembryonic antigen in gastric juice collected during endoscopy. Value in detecting highârisk patients and gastric cancer
NITTI, DONATO;Di Mario, F.;
1983-01-01
Abstract
In order to ascertain the role of gastric carcinoembryonic antigen (CEA) determination in detecting patients with a risk for gastric cancer, 69 subjects were studied; 23 were referred for endoscopy because of dyspepsia but without obvious macroscopic lesions, 27 with duodenal ulcer, 11 with benign gastric ulcer, 8 with gastric cancer. The following results were obtained by subdividing the material according to the histologic interpretation of the results of gastric mucosal biopsies: (1) in the presence of minor histologic abnormalities of the gastric mucosa, CEA in gastric juice was under 100 ng/ml in all but five cases; and (2) in moderate or severe chronic atrophic gastritis (associated or otherwise with intestinal metaplasia or dysplasia), and in gastric cancer, gastric CEA ranged between 224 and 3120 ng/ml in all but two cases. Although not diagnostic for gastric cancer, gastric CEA is a promising test in detecting patients at risk, including those with dysplasia of the gastric mucosa. Cancer 52:2334â2337, 1983. Copyright © 1983 American Cancer SocietyI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
