An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex. © 1994 Excerpta Medica, Inc. All rights reserved.

Are morphology and composition of gallstones related? An x-ray diffraction study / Bassi, N.; Del Favero, G.; Meggiato, T.; Scalon, P.; Ghiro, S.; Molin, M.; Pilotto, A.; Vigneri, S.; Savarino, V.; Mela, G. S.; Di Mario, F.. - In: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL. - ISSN 0011-393X. - 55:10(1994), pp. 1169-1175. [10.1016/S0011-393X(05)80257-7]

Are morphology and composition of gallstones related? An x-ray diffraction study

Bassi, N.;Pilotto, A.;Di Mario, F.
1994

Abstract

An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex. © 1994 Excerpta Medica, Inc. All rights reserved.
Are morphology and composition of gallstones related? An x-ray diffraction study / Bassi, N.; Del Favero, G.; Meggiato, T.; Scalon, P.; Ghiro, S.; Molin, M.; Pilotto, A.; Vigneri, S.; Savarino, V.; Mela, G. S.; Di Mario, F.. - In: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL. - ISSN 0011-393X. - 55:10(1994), pp. 1169-1175. [10.1016/S0011-393X(05)80257-7]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2844337
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