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EnglishThis study analyzed the relationship between Helicobacter pylori infection, mucosal gastrin concentration, and basal serum gastrin levels in duodenal ulcer patients with dyspepsia. Patients with duodenal ulcers who were H pylori positive showed higher antral gastrin concentrations than either H pylori-positive patients with dyspepsia or H pylori-negative patients with duodenal ulcers. No correlation was found between serum gastrin and antral gastrin concentrations. The increased antral gastrin concentrations were not correlated with an inhibition of acid-gastrin feedback. These preliminary data confirm that H pylori infection impairs gastrin physiology. © 1994 Excerpta Medica, Inc. All rights reserved.
A preliminary report on Helicobacter pylori and antral gastrin concentration in patients with duodenal ulcer / Vianello, F.; Germanà, B.; Plebani, M.; Dotto, P.; Del Bianco, T.; Laino, G.; Dal Santo, P.; Battaglia, G.; Dal Bö, N.; Salandin, S.; Ferrana, M.; Rugge, M.; Di Mario, F.. - In: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL. - ISSN 0011-393X. - 55:1(1994), pp. 1-7. [10.1016/S0011-393X(05)80071-2]
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