This study analyzed the relationship between Helicobacter pylori infection, mucosal gastrin concentration, and basal serum gastrin levels in duodenal ulcer patients with dyspepsia. Patients with duodenal ulcers who were H pylori positive showed higher antral gastrin concentrations than either H pylori-positive patients with dyspepsia or H pylori-negative patients with duodenal ulcers. No correlation was found between serum gastrin and antral gastrin concentrations. The increased antral gastrin concentrations were not correlated with an inhibition of acid-gastrin feedback. These preliminary data confirm that H pylori infection impairs gastrin physiology. © 1994 Excerpta Medica, Inc. All rights reserved.
A preliminary report on Helicobacter pylori and antral gastrin concentration in patients with duodenal ulcer / Vianello, F., Germanà, B., Plebani, M., Dotto, P., Del Bianco, T., Laino, G., Dal Santo, P., Battaglia, G., Dal Bö, N., Salandin, S., Ferrana, M., Rugge, M., Di Mario, F.. - In: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL. - ISSN 0011-393X. - 55:1(1994), pp. 1-7. [10.1016/S0011-393X(05)80071-2]
A preliminary report on Helicobacter pylori and antral gastrin concentration in patients with duodenal ulcer
Battaglia, G.;Di Mario, F.
1994-01-01
Abstract
This study analyzed the relationship between Helicobacter pylori infection, mucosal gastrin concentration, and basal serum gastrin levels in duodenal ulcer patients with dyspepsia. Patients with duodenal ulcers who were H pylori positive showed higher antral gastrin concentrations than either H pylori-positive patients with dyspepsia or H pylori-negative patients with duodenal ulcers. No correlation was found between serum gastrin and antral gastrin concentrations. The increased antral gastrin concentrations were not correlated with an inhibition of acid-gastrin feedback. These preliminary data confirm that H pylori infection impairs gastrin physiology. © 1994 Excerpta Medica, Inc. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
