An endoscopically controlled clinical trial on maintenance Ranitidine treatment of scarred duodenal ulcer was carried out in 78 patients, randomly allocated to either 150 mg Ranitidine at night or low-dose antacid when necessary in a 1-year follow-up study. The maintenance Ranitidine regime prevented ulcer relapse in 23 of 31 cases (74.2%), without any significant adverse reaction. In the control group, the relapse was prevented in 12 of 30 cases (40%); the difference was found to be statistically significant.
Ranitidine in long-term duodenal ulcer treatment: A multicentre trial / Di Mario, F.; Albano, O.; Angelini, G.; Cavallini, G.; Doronzo, F.; Farini, R.; Francavilla, A.; Naccarato, R.; Scuro, L. A.; Vianello, F.. - In: DIGESTION. - ISSN 0012-2823. - 24:4(1982), pp. 260-263. [10.1159/000198806]
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