Throughout the human life, the gut microbiota interacts with us in a number of different ways, thereby influencing our health status. The acquisition of such an interactive gut microbiota commences at birth. Medical and environmental factors including diet, antibiotic exposure and mode of delivery are major factors that shape the composition of the microbial communities in the infant gut. Among the most abundant members of the infant microbiota are species belonging to the Bifidobacterium genus, which are believed to confer beneficial effects upon their host. Bifidobacteria may be acquired directly from the mother by vertical transmission and their persistence in the infant gut is associated with their saccharolytic activity toward glycans that are abundant in the infant gut. Here, we discuss the establishment of the infant gut microbiota and the contribution of bifidobacteria to this early life microbial consortium.

Bifidobacteria and the infant gut: an example of co-evolution and natural selection / Turroni, Francesca; Milani, Christian; Duranti, Sabrina; Ferrario, Chiara; Lugli, Gabriele Andrea; Mancabelli, Leonardo; van Sinderen, Douwe; Ventura, Marco. - In: CELLULAR AND MOLECULAR LIFE SCIENCES. - ISSN 1420-682X. - 75:1(2018), pp. 103-118. [10.1007/s00018-017-2672-0]

Bifidobacteria and the infant gut: an example of co-evolution and natural selection

Turroni, Francesca;Milani, Christian;Duranti, Sabrina;Ferrario, Chiara;Lugli, Gabriele Andrea;Mancabelli, Leonardo;van Sinderen, Douwe;Ventura, Marco
2018

Abstract

Throughout the human life, the gut microbiota interacts with us in a number of different ways, thereby influencing our health status. The acquisition of such an interactive gut microbiota commences at birth. Medical and environmental factors including diet, antibiotic exposure and mode of delivery are major factors that shape the composition of the microbial communities in the infant gut. Among the most abundant members of the infant microbiota are species belonging to the Bifidobacterium genus, which are believed to confer beneficial effects upon their host. Bifidobacteria may be acquired directly from the mother by vertical transmission and their persistence in the infant gut is associated with their saccharolytic activity toward glycans that are abundant in the infant gut. Here, we discuss the establishment of the infant gut microbiota and the contribution of bifidobacteria to this early life microbial consortium.
Bifidobacteria and the infant gut: an example of co-evolution and natural selection / Turroni, Francesca; Milani, Christian; Duranti, Sabrina; Ferrario, Chiara; Lugli, Gabriele Andrea; Mancabelli, Leonardo; van Sinderen, Douwe; Ventura, Marco. - In: CELLULAR AND MOLECULAR LIFE SCIENCES. - ISSN 1420-682X. - 75:1(2018), pp. 103-118. [10.1007/s00018-017-2672-0]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2838339
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