We report a 9-year-old boy, with childhood cerebral X-linked adrenoleukodystrophy (CCALD), presenting with an episode of loss of consciousness, fixed gaze, hypotonia and vomit with spontaneous resolution and post-ictal sleep. Behavioural impairment has been observed since the previous five months. Magnetic Resonance Images (MRI) revealed isolated bilateral, symmetric, confluent temporal white matter lesions involving also corticospinal tracts, with sparing of the parieto-occipital and frontal white matter. This report outlines an atypical neuroradiological localization of X-linked adrenoleukodystrophy and neuropsychological findings not specifically related to the brain involvement seen at the MRI.
A novel temporal pattern of childhood cerebral X-linked adrenoleukodystrophy / Turco, Emanuela C.; Ormitti, Francesca; Andreolli, Anna; Barsacchi, Marina; Facini, Carlotta; Pisani, Francesco. - In: BRAIN & DEVELOPMENT. - ISSN 0387-7604. - 40:3(2018), pp. 238-241. [10.1016/j.braindev.2017.10.005]
A novel temporal pattern of childhood cerebral X-linked adrenoleukodystrophy
Turco, Emanuela C.;Ormitti, Francesca;Andreolli, Anna;Barsacchi, Marina;Facini, Carlotta;Pisani, Francesco
2018-01-01
Abstract
We report a 9-year-old boy, with childhood cerebral X-linked adrenoleukodystrophy (CCALD), presenting with an episode of loss of consciousness, fixed gaze, hypotonia and vomit with spontaneous resolution and post-ictal sleep. Behavioural impairment has been observed since the previous five months. Magnetic Resonance Images (MRI) revealed isolated bilateral, symmetric, confluent temporal white matter lesions involving also corticospinal tracts, with sparing of the parieto-occipital and frontal white matter. This report outlines an atypical neuroradiological localization of X-linked adrenoleukodystrophy and neuropsychological findings not specifically related to the brain involvement seen at the MRI.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
