Obesity is associated with an increased risk of type 2 diabetes and cardiovascular complications. The risk depends significantly on adipose tissue distribution. Liraglutide, a glucagon-like peptide 1 analog, is associated with weight loss, improved glycemic control, and reduced cardiovascular risk. We determined whether an equal degree of weight loss by liraglutide or lifestyle changes has a different impact on subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in obese subjects with prediabetes or early type 2 diabetes.

Effects of Liraglutide on Weight Loss, Fat Distribution, and β-Cell Function in Obese Subjects With Prediabetes or Early Type 2 Diabetes / Santilli, F., Simeone, P.G., Guagnano, M.T., Leo, M., Maccarone, M.T., Di Castelnuovo, A., Sborgia, C., Bonadonna, R., Angelucci, E., Federico, V., Cianfarani, S., Manzoli, L., Davì, G., Tartaro, A., Consoli, A.. - In: DIABETES CARE. - ISSN 0149-5992. - (2017), p. dc170589. [10.2337/dc17-0589]

Effects of Liraglutide on Weight Loss, Fat Distribution, and β-Cell Function in Obese Subjects With Prediabetes or Early Type 2 Diabetes

BONADONNA, Riccardo;
2017-01-01

Abstract

Obesity is associated with an increased risk of type 2 diabetes and cardiovascular complications. The risk depends significantly on adipose tissue distribution. Liraglutide, a glucagon-like peptide 1 analog, is associated with weight loss, improved glycemic control, and reduced cardiovascular risk. We determined whether an equal degree of weight loss by liraglutide or lifestyle changes has a different impact on subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in obese subjects with prediabetes or early type 2 diabetes.
2017
Effects of Liraglutide on Weight Loss, Fat Distribution, and β-Cell Function in Obese Subjects With Prediabetes or Early Type 2 Diabetes / Santilli, F., Simeone, P.G., Guagnano, M.T., Leo, M., Maccarone, M.T., Di Castelnuovo, A., Sborgia, C., Bonadonna, R., Angelucci, E., Federico, V., Cianfarani, S., Manzoli, L., Davì, G., Tartaro, A., Consoli, A.. - In: DIABETES CARE. - ISSN 0149-5992. - (2017), p. dc170589. [10.2337/dc17-0589]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2832518
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