To achieve the post-2015 global tuberculosis target of 90% reduction in tuberculosis incidence by 2035, the present rate of decline must accelerate. Among factors that hinder tuberculosis control, malnutrition and diabetes are key challenges. We review available data to describe the complex relationship between tuberculosis, diabetes, and nutritional status. Additionally, we review past trends, present burden, and available future global projections for diabetes, overweight and obesity, as well as undernutrition and food insecurity. Using a mathematical model, we estimate the potential effect of these factors on tuberculosis burden up to 2035. Great potential exists for reduction of worldwide tuberculosis burden by combination of improved prevention and care of diabetes with reduction of undernutrition. To achieve this combination will require joint efforts and strong cross-programme links, enabling synergistic effects of public health policies that promote good nutrition and optimum clinical care for tuberculosis and diabetes.

The effect of diabetes and undernutrition trends on reaching 2035 global tuberculosis targets / Odone, Anna; Houben, Rein M. G. J; White, Richard G; Lönnroth, Knut. - In: THE LANCET DIABETES & ENDOCRINOLOGY. - ISSN 2213-8587. - 2:9(2014), pp. 754-764. [10.1016/S2213-8587(14)70164-0]

The effect of diabetes and undernutrition trends on reaching 2035 global tuberculosis targets

ODONE, Anna;
2014

Abstract

To achieve the post-2015 global tuberculosis target of 90% reduction in tuberculosis incidence by 2035, the present rate of decline must accelerate. Among factors that hinder tuberculosis control, malnutrition and diabetes are key challenges. We review available data to describe the complex relationship between tuberculosis, diabetes, and nutritional status. Additionally, we review past trends, present burden, and available future global projections for diabetes, overweight and obesity, as well as undernutrition and food insecurity. Using a mathematical model, we estimate the potential effect of these factors on tuberculosis burden up to 2035. Great potential exists for reduction of worldwide tuberculosis burden by combination of improved prevention and care of diabetes with reduction of undernutrition. To achieve this combination will require joint efforts and strong cross-programme links, enabling synergistic effects of public health policies that promote good nutrition and optimum clinical care for tuberculosis and diabetes.
The effect of diabetes and undernutrition trends on reaching 2035 global tuberculosis targets / Odone, Anna; Houben, Rein M. G. J; White, Richard G; Lönnroth, Knut. - In: THE LANCET DIABETES & ENDOCRINOLOGY. - ISSN 2213-8587. - 2:9(2014), pp. 754-764. [10.1016/S2213-8587(14)70164-0]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2822972
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 82
  • ???jsp.display-item.citation.isi??? 84
social impact