This paper describes a bio-sensor based on a functionalized microstructured optical fiber with a Bragg grating, for specific DNA target sequences detection. The inner surface of the fiber has been functionalized using PNA probes that allows hybridization of the target DNA. To achieve sensing enhancement, functionalized gold nanoparticles were used. Experimental measurements show the high selectivity and sensitivity of the bio-sensor.
Fiber-Based Biosensors for DNA Detection / Barozzi, Matteo; Al Hayali, Sarah K. M.; Candiani, Alessandro; Vannucci, Armando; Al Janabi, A. Haidi; Cucinotta, Annamaria; Selleri, Stefano. - STAMPA. - (2016), pp. 549-552. (Intervento presentato al convegno XXI RINEM Riunione Nazionale di Elettromagnetismo tenutosi a Parma, Italy nel September 12-14, 2016).
Fiber-Based Biosensors for DNA Detection
BAROZZI, Matteo;CANDIANI, Alessandro;VANNUCCI, Armando;CUCINOTTA, Annamaria;SELLERI, Stefano
2016-01-01
Abstract
This paper describes a bio-sensor based on a functionalized microstructured optical fiber with a Bragg grating, for specific DNA target sequences detection. The inner surface of the fiber has been functionalized using PNA probes that allows hybridization of the target DNA. To achieve sensing enhancement, functionalized gold nanoparticles were used. Experimental measurements show the high selectivity and sensitivity of the bio-sensor.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
